Reza Afshari

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Drugs and chemicals are almost easily available in Iran. Natural toxins as poisonous plants and animals also exist in most parts of the country. Therefore, acute poisonings, either intentional or accidental and also drug abuse/addiction are common in Iran. In spite of these difficulties there is no center for poison control and surveillance in this country(More)
We investigated the effects of antioxidant activity of safranal, a constituent of Crocus sativus L., against lung oxidative damage in diabetic rats. The rats were divided into the following groups of 8 animals each: control, diabetic, and three diabetic + safranal-treated (0.25, 0.50, and 0.75 mg/kg/day) groups. Streptozotocin (STZ) was injected(More)
AIMS To examine the effect of licence change for thioridazine at the end of 2000 on the prescription of antipsychotic drugs in England and Scotland, and investigate changes in poisons information inquiries and, for Edinburgh, poisons admissions. METHODS Prescription data for antipsychotic drugs were obtained for England and Scotland and quarterly trends(More)
Thallium (Tl) is a toxic heavy metal that exists in nature. Tl poisoning (thallotoxicosis) may occur in opioid addicts. This study was designed to evaluate the frequency and level of urinary Tl in opioid abusers. In addition, clinical findings were evaluated. A total of 150 subjects were examined. Cases with a history of at least 3 years of abuse were(More)
Opioid abuse is common in Iran. In 2005, a new version of locally produced illicit opioid vials, so called Norgesic, appeared in the illicit market, which gained popularity rapidly and led to an improvement of stigmatizing the general appearance of dependent cases. Later, some cases suffered Cushing's-like problems. A prospective case series was designed to(More)
Worldwide, lung cancer is the most common form of cancer. Saffron has been used in folk medicine for centuries. We investigated the potential of saffron to induce cytotoxic and apoptotic effects in lung cancer cells (A549). We also examined the caspase-dependent pathways activation of saffron-induced apoptosis against the A549 cells. A549 cells were(More)
BACKGROUND Occupational lead poisoning is a health problem in Iran. It has not previously been studied in traditional tile makers. OBJECTIVE To determine the prevalence of lead poisoning and its complications in traditional tile workers in Mashhad, Northwest of Iran. METHODS We visited workers in two traditional tile factories and collected data by(More)
| April 2015 | 420 world but lower than natural Chinese soils and Canadian guidelines.[3,5,9] There have been some attempts to establish guidance for preventive measures related to lead pollution and toxicity in Iran. Physicians should be aware of potential consequences related to chronic thallium and lead toxicities in some regions. Sporadic refractory(More)
BACKGROUND Spider (Latrodectus tredecimguttatus) bites are relatively common in North East Iran. They induce morbidity and rarely mortality. We aimed to investigate clinical, electrocardiographic and para-clinical changes in patients with this bite. METHODS All consecutive patients admitted with suspected spider bites between September 2005 and September(More)