Resit Canbeyli

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This study aimed to show the difference of epilepsy from another chronic neurological disorder with episodic manifestations (CDEM): migraine. Seventy persons with epilepsy (PWE), 56 persons with migraine (PWM) and 45 healthy control participants (HCs) were included. The groups were compared in terms of demographics, quality of life, depression and(More)
The present study investigated the effect of a single, anesthetic dose of ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) glutamate receptor antagonist, on behavioral despair, an animal model of depression. Separate groups of male Wistar rats injected with an anesthetic dose of ketamine (160 mg/kg ip) and tested 3, 7, or 10 days later showed(More)
OBJECTIVE Cytokine based immunotherapy has long been an exciting field for many investigators aiming to provide an effective alternative treatment modality for glioma management. Among these cytokines, interleukin-12 (IL-72) plays a crucial role in mediating inflammatory and antitumoral activity on the host defence. We have investigated the therapeutic role(More)
PURPOSE To evaluate changes in intractable epilepsy patients in terms of quality of life, depression, anxiety, stigma, and impact of epilepsy before and after surgery. METHODS Twenty patients with intractable temporal lobe epilepsy who were waiting for surgery (pre-SAH group) and 21 patients who had already undergone surgery (post-SAH group) were studied.(More)
Separate groups of female Wistar rats were tested every three months over a year to assess the extent of seasonal variability in the behavioral despair model of depression consisting of 2 swim tests separated by 24 h. There was a significant seasonal variability in the duration of immobility in the swim tests; duration of immobility was shorter in August(More)
Depression involves a dysfunction in an affective fronto-limbic circuitry including the prefrontal cortices, several limbic structures including the cingulate cortex, the amygdala, and the hippocampus as well as the basal ganglia. A major emphasis of research on the etiology and treatment of mood disorders has been to assess the impact of centrally(More)
This study investigated the effects of stimulus modality, standard duration, sex, and laterality in duration discrimination by musicians and nonmusicians. Seventeen musicians (M age = 24.1 yr.) and 22 nonmusicians (M age = 26.8 yr.) participated. Auditory (1,000 Hz) and tactile (250 Hz) sinusoidal suprathreshold stimuli with varying durations were used. The(More)
The authors investigated 3 aspects of the learned helplessness (LH) phenomenon: the induction of helplessness in humans by a new instrumental task, the effects of a therapy technique that relies on direct retroactive reevaluation of the helplessness experience, and the role of personality characteristics in both helplessness induction and therapy. The(More)
To evaluate the role of the hypothalamus in hypertension, we compared the. development of blood pressure (BP) in normotensive host rats grafted at weaning with fetal hypothalamus from genetically hypertensive or normotensive donors. The anteroventral region of the third ventricle (AV3V) has been implicated in the control of BP, such that lesions of AV3V(More)
The bed nucleus of the stria terminalis (BNST) was lesioned in adult male Wistar rats (n = 9) and its involvement in coping behavior during forced swim stress examined. Rats remain immobile longer in the second of two swim tests, a phenomenon known as learned despair. Results revealed that, compared to sham-operated controls (n = 8), BNST-lesioned animals(More)