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The generation of biologically active proteins by regulated intramembrane proteolysis is a highly conserved mechanism in cell signaling. Presenilin-dependent gamma-secretase activity is responsible for the intramembrane proteolysis of selected type I membrane proteins, including beta-amyloid precursor protein (APP) and Notch. A small fraction of(More)
Children's thinking about diversity of belief in 4 realms--morality, taste, facts, and ambiguous facts--was examined. Ninety-six participants (ages 5, 7, and 9) were interviewed about beliefs different from their own that were endorsed by characters with different status; their judgments of relativism, tolerance, and disagreeing persons were assessed.(More)
It's hard to argue against the concepts of self-describing data, contextual interfaces, and richer metadata for content that eventually will make up the Semantic Web. The need is just so great, and becomes greater by the day with the huge increase in unstructured content and non-integrated data repositories. However, it is easy to imagine semantic(More)
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