Rene V Allard

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OBJECTIVE To evaluate the tolerability and efficacy of tapentadol immediate release (IR) and oxycodone IR for relief of moderate to severe pain in elderly and nonelderly patients. METHODS Post hoc data analyses were conducted on a 90-day randomized, phase 3, double-blind, flexible-dose study ( NCT00364546) of adults with moderate to(More)
BACKGROUND We assessed associations between intraoperative neuraxial block and postoperative epidural analgesia, and a composite primary outcome of death or non-fatal myocardial infarction, at 30 days post-randomization in POISE-2 Trial subjects. METHODS 10 010 high-risk noncardiac surgical patients were randomized aspirin or placebo and clonidine or(More)
To the Editor, The ability to teach direct laryngoscopy effectively poses a challenge to medical educators. A key difficulty is the inability of the instructor and trainee to visualize the laryngoscopy field of view simultaneously. The ability of the instructor to see what the trainee is seeing would allow for real-time feedback without interference with(More)
BACKGROUND The PeriOperative ISchemia Evaluation-2 (POISE-2) trial compared aspirin with placebo after noncardiac surgery. METHODS The authors randomly assigned 10,010 patients undergoing noncardiac surgery to receive 200 mg aspirin or placebo 2 to 4 h before surgery and then 100 mg aspirin daily or placebo daily for up to 30 days after surgery. Herein,(More)
PURPOSE We report a case of unrecognized cardiac tamponade diagnosed pre-induction by focused transthoracic echocardiography (TTE). The value of focused perioperative TTE, the anesthetic implications of Churg-Strauss syndrome, and the diagnosis of cardiac tamponade are discussed. CLINICAL FEATURES A 58-yr-old man with a history of severe asymptomatic(More)