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AIMS A randomized, double-blind study with a high dose of digoxin administered intravenously for conversion of atrial fibrillation (not due to haemodynamic alternations) to sinus rhythm, and for rate control in converters and non-converters was set up. Outcome measures were conversion within 12 h; time to conversion; early rate control; and stable slowing(More)
PURPOSE To identify procedural parameters predicting recurrence of atrial fibrillation (AF) after a first circumferential pulmonary vein isolation (CPVI). METHODS One hundred seventy-one patients undergoing CARTO-guided CPVI for recurrent AF with a left atrial (LA) diameter <45 mm were studied. Follow-up (symptoms and 7-day Holter) was performed at 1 and(More)
BACKGROUND The recent availability of implantable cardioverter-defibrillators (ICDs) that record 1024 R-R intervals preceding a ventricular tachyarrhythmia (VTA) provides a unique opportunity to analyze heart rate variability (HRV) before the onset of VTA. METHODS AND RESULTS Fifty-eight post-myocardial infarction patients with an implanted ICD for(More)
AIMS The purpose of this study was to assess risk factors for sudden death after discharge from hospital for myocardial infarction in an era in which 50% of patients receive thrombolytic drugs. METHODS AND RESULTS We prospectively studied 708 consecutive survivors of myocardial infarction admitted to hospitals, which had registered their clinical,(More)
OBJECTIVE To study differences between repetitive monomorphic ventricular tachycardia (RMVT) of right ventricular origin, and ventricular tachycardia in arrhythmogenic right ventricular dysplasia (ARVD). PATIENTS Consecutive groups with RMVT (n = 15) or ARVD (n = 12), comparable for age and function. METHODS Analysis of baseline, tachycardia, and signal(More)
OBJECTIVE To relate QT parameters to infarct size and inducibility during electrophysiological studies. DESIGN Analysis of a prospective register. SETTING University hospital. PATIENTS 64 patients with coronary artery disease and documented life threatening ventricular arrhythmias. INTERVENTIONS Measurements of QT-max, QTc-max, and QT dispersion(More)
Assessment of autonomic tone preceding the onset of atrial fibrillation (AF) after coronary artery bypass grafting (CABG) with heart rate variability was examined in 64 patients scheduled for elective CABG (days 2 to 5). Ninety-six-hour Holter tapes were analyzed in each patient and all events labeled by an experienced technician. The hour preceding AF was(More)
OBJECTIVES To evaluate a possible effect of lipid lowering drugs on recurrences of ventricular arrhythmias (VA) after implantable cardioverter defibrillator (ICD) implantation. BACKGROUND In patients with coronary artery disease (CAD), lipid lowering drugs reduce total and sudden cardiac death. Because the mechanism is not completely understood, we(More)