Renato Maia Guimarães

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To address the pending public health crisis due to Alzheimer's disease (AD) and related neurodegenerative disorders, the Marian S. Ware Alzheimer Program at the University of Pennsylvania held a meeting entitled "State of the Science Conference on the Advancement of Alzheimer's Diagnosis, Treatment and Care," on June 21-22, 2012. The meeting comprised four(More)
UNLABELLED Frailty tends to be considered as a major risk for adverse outcomes in older persons, but some important aspects remain matter of debate. OBJECTIVES The purpose of this paper is to present expert's positions on the main aspects of the frailty syndrome in the older persons. PARTICIPANTS Workshop organized by International Association of(More)
IAGG, WHO, and SFGG organized a international workshop on Health promotion programs on prevention of late on-set dementia. Thirty world specialists coming from Europe, North America, Asia, South America, Africa and Australia, shared their experience on methods and results of large epidemiological interventions to reduce incidents of dementia or delay its(More)
OBJECTIVE To analyze cytomorphologically the buccal mucosa of patients with Alzheimer's disease (AD). STUDY DESIGN Brush biopsies were obtained from 10 patients with AD and 9 age-matched controls without neurologic symptoms from 3 distinct oral sites. RESULTS A significant reduction in partially keratinized intermediate (red) cells was observed in the(More)
BACKGROUND The difference in individual ageing remains a not fully understood subject. OBJECTIVE To discuss the use of the health capital concept and its application to the life course approach as an alternative to understand factors involved on individual ageing and identify genetic, socioeconomic, psychological and biological influences. RESULTS The(More)
ticipants and their families. The local ethics committee approved the study. The urinary questionnaire showed that daytime urinary frequency (>8 times), nighttime urinary frequency (>twice), and urinary incontinence (>1/wk) was most common in WMLs alone (33%, 44%, 33% in AD alone; 40%, 60%, 27% in AD + WMLs; 68%, 84%, 40% in WMLs alone, respectively (Figure(More)
OBJECTIVE To determine the incidence of sleep disorder at a follow-up examination from 1 to 4 years, in demented patients diagnosed at first visit, besides analyzing associated demographic and comorbidities characteristics. METHODS A total of 122 elderly patients aged 60 years or older and diagnosed with dementia (Alzheimer and other) were followed in a(More)
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