Renata Novak Kujundzic

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BORIS is a paralog of a highly conserved, multi-functional chromatin factor CTCF. Unlike CTCF, which has been shown to possess tumor-suppressive properties, BORIS belongs to the “cancer/testis antigen” family normally expressed only in germ cells and aberrantly activated in a variety of tumors. The consequences of BORIS expression, relative abundance of its(More)
EpigeneƟ cs is focused on gene physiology, analyzing inherited variaƟ ons in gene expression, while genomics is focused on gene anatomy, analyzing gene structure. DNA methylaƟ on and histone post-translaƟ onal modifi caƟ ons are the basic epigeneƟ c mechanisms regulaƟ ng gene acƟ vity. These two processes complement each other, creaƟ ng an epigeneƟ c(More)
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