Renata Novak Kujundzic

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The mechanisms of beneficial preventive and therapeutic effects achieved by traditional and complementary medicine are currently being deciphered in molecular medicine. Curcumin, a yellow-colored polyphenol derived from the rhizome of turmeric (Curcuma longa), influences a wide variety of cellular processes through the reshaping of many molecular targets.(More)
BORIS is a paralog of a highly conserved, multi-functional chromatin factor CTCF. Unlike CTCF, which has been shown to possess tumor-suppressive properties, BORIS belongs to the “cancer/testis antigen” family normally expressed only in germ cells and aberrantly activated in a variety of tumors. The consequences of BORIS expression, relative abundance of its(More)
The influence of de novo synthesis of nicotinamide adenine dinucleotide (NAD) through the kynurenine (KYN) pathway of tryptophan (TRP) degradation on gene transcription of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in chicken interferon gamma (ChIFN-gamma)-stimulated and non-stimulated chicken macrophage cell line HD11 was(More)
EpigeneƟ cs is focused on gene physiology, analyzing inherited variaƟ ons in gene expression, while genomics is focused on gene anatomy, analyzing gene structure. DNA methylaƟ on and histone post-translaƟ onal modifi caƟ ons are the basic epigeneƟ c mechanisms regulaƟ ng gene acƟ vity. These two processes complement each other, creaƟ ng an epigeneƟ c(More)
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