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  • Søren Kragh Moestrup, Renata Kozyraki, +8 authors Pierre J. Verroust
  • Biology, Medicine
  • The Journal of biological chemistry
  • 1998 (First Publication: 27 February 1998)
  • The present report shows the molecular characterization of the rat 460-kDa epithelial glycoprotein that functions as the receptor facilitating uptake of intrinsic factor-vitamin B12 complexes in theContinue Reading
  • Renata Kozyraki, John Fyfe, +9 authors Søren Kragh Moestrup
  • Medicine
  • Nature Medicine
  • 1999 (First Publication: 1 June 1999)
  • Cubilin is the intestinal receptor for the endocytosis of intrinsic factor–vitamin B12. However, several lines of evidence, including a high expression in kidney and yolk sac, indicate it may haveContinue Reading
  • Gwénaëlle Coudroy, Jakub Gburek, +5 authors Michèle Maurice
  • Medicine, Biology
  • Journal of the American Society of Nephrology…
  • 2005 (First Publication: 29 June 2005)
  • Cubilin is a peripheral apical membrane receptor for multiple ligands that are taken up in several absorptive epithelia. Recently, amnionless (AMN) was identified to form a functional receptorContinue Reading
  • Renata Kozyraki, Merete Kristiansen, +5 authors Søren Kragh Moestrup
  • Biology, Medicine
  • Blood
  • 1998 (First Publication: 15 May 1998)
  • Uptake of vitamin B12 (cyanocobalamin) is facilitated by the cobalamin-binder gastric intrinsic factor (IF), which recognizes a 460-kD receptor, cubilin, present in the epithelium of intestine andContinue Reading
  • Emeline Assémat, François P. Châtelet, +4 authors Renata Kozyraki
  • Biology, Medicine
  • Gene expression patterns : GEP
  • 2005 (First Publication: 1 December 2005)
  • Cubilin and megalin are multiligand epithelial endocytic receptors well characterized in the adult kidney and ileum where they form a complex essential for protein, lipid and vitamin uptake. AlthoughContinue Reading