Sort by:

• Highly Influential Citations
• Citations
• Acceleration
• Velocity
• Recency

Learn More

Initial structure-activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA1/LPA3 receptor antagonist.

• Brian H Heasley, Renata Jarosz, Kevin R. Lynch, Timothy L. Macdonald
• Bioorganic & medicinal chemistry letters
• 2004

A recently reported dual LPA1/LPA3 receptor antagonist (VPC12249, 1) has been modified herein so as to optimize potency and selectivity at LPA receptors. Compounds containing variation in the acyl… (More)

Functional electrical stimulation in spinal cord injury respiratory care.

• Renata Jarosz, Meagan M Littlepage, G. H. Creasey, Stephen L McKenna
• Topics in spinal cord injury rehabilitation
• 2012

The management of chronic respiratory insufficiency and/or long-term inability to breathe independently has traditionally been via positive-pressure ventilation through a mechanical ventilator.… (More)

Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor.

• Yutaka Hasegawa, James R Erickson, +11 authors Xianjun Fang
• The Journal of biological chemistry
• 2003

Lysophosphatidic acid (LPA) is a bioactive lysophospholipid mediator that acts through G protein-coupled receptors. Most cell lines in culture express one or more LPA receptors, making it difficult… (More)

A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonist.

• Brian H Heasley, Renata Jarosz, Karen M Carter, Seyoung Van, Kevin R. Lynch, Timothy L. Macdonald
• Bioorganic & medicinal chemistry letters
• 2004

A recently reported dual LPA(1)/LPA(3) receptor antagonist (1) has been modified so as to modulate the basicity, sterics, and dipole moment of the 2-pyridyl moiety. Additionally, the implications of… (More)

Physical performance analysis: A new approach to assessing free-living physical activity in musculoskeletal pain and mobility-limited populations

• Mathew Smuck, Christy C Tomkins-Lane, Ma Agnes Martinez Ith, Renata Jarosz, Ming-Chih Kao
• PloS one
• 2017

BACKGROUND Accurate measurement of physical performance in individuals with musculoskeletal pain is essential. Accelerometry is a powerful tool for this purpose, yet the current methods designed to… (More)

Eccentric loading and upper limb muscle-bone asymmetries in elite tennis players.

• Marko Bodor, Renata Jarosz
• Medicine and science in sports and exercise
• 2015

We read with interest the comprehensive and excellent study ‘‘Upper limb muscle–bone asymmetries and bone adaptation in elite youth tennis players’’ by Ireland et al. (2). One of their most important… (More)

Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid.

• Webster L Santos, Brian H Heasley, Renata Jarosz, Karen M Carter, Kevin R. Lynch, Timothy L. Macdonald
• Bioorganic & medicinal chemistry letters
• 2004

Using an N-oleoyl ethanolamide scaffold, a series of phosphate polar head group analogues of LPA comprised of various alpha-substituted phosphonates and thiophosphates was prepared. In a broken cell… (More)

Racial differences in the anatomical distribution of colon cancer.

• Christoforos Thomas, Renata Jarosz, Nathan Evans
• Archives of surgery
• 1992

The objective of this study was to determine whether racial differences exist with regard to the anatomical distribution of adenocarcinoma of the colon. We conducted a retrospective study of… (More)

Determinants of physical activity in America: a first characterization of physical activity profile using the National Health and Nutrition Examination Survey (NHANES).

• Ming-Chih Kao, Renata Jarosz, Michael A. Goldin, Amy K Patel, Mathew Smuck
• PM & R : the journal of injury, function, and…
• 2014

OBJECTIVES To develop and implement methodologies for characterizing accelerometry-derived patterns of physical activity (PA) in the United States in relation to demographics, anthropometrics,… (More)

• ‹
• 1
• ›