Renata Cristina Picão

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Multi-drug efflux pumps have been increasingly recognized as a major component of resistance in P. aeruginosa. We have investigated the expression level of efflux systems among clinical isolates of P. aeruginosa, regardless of their antimicrobial susceptibility profile. Aztreonam exhibited the highest in vitro activity against the P. aeruginosa isolates(More)
OBJECTIVES To search for plasmid-mediated qnr genes among waterborne environmental Aeromonas spp. recovered from Switzerland. METHODS Isolates presenting MICs of nalidixic acid or ciprofloxacin > or = 1 mg/L were screened for qnr genes by a multiplex PCR approach followed by sequencing. Plasmids were transferred by transformation, and further analysis of(More)
The emergence of metallo-beta-lactamase (MBL)-producing isolates is a challenge to routine microbiology laboratories, since there are no standardized methods for detecting such isolates. The aim of this study was to evaluate the accuracy of different phenotypic methods to detect MBL production among Pseudomonas spp., Acinetobacter spp., and enterobacterial(More)
OBJECTIVES The aim of this study was to evaluate the presence of carbapenemases in a Klebsiella pneumoniae collection and the performance of the modified Hodge test (MHT) to correctly identify this phenotype. METHODS Twenty-eight K. pneumoniae clinical isolates with reduced susceptibility to carbapenems were evaluated. Antimicrobial susceptibility and(More)
A retrospective survey was conducted to characterize beta-lactamases in a collection of 43 ceftazidime-resistant Pseudomonas aeruginosa isolates recovered from patients with bloodstream infections hospitalized at a Brazilian teaching hospital between January and December 2005. Resistance rates for carbapenems, aminoglycosides, and quinolones were over 80%,(More)
The immune cross-reactivity between Trypanosoma cruzi, the protozoan that causes Chagas' disease, and Phytomonas serpens, a trypanosomatid that infects tomatoes, was studied. Sera from patients with Chagas' disease presented a strong reactivity with P. serpens antigens by conventional serological assays such as indirect immunofluorescence (IIF) and direct(More)
Klebsiella pneumoniae is an important opportunistic pathogen associated with nosocomial and community-acquired infections. A wide repertoire of virulence and antimicrobial resistance genes is present in K. pneumoniae genomes, which can constitute extra challenges in the treatment of infections caused by some strains. K. pneumoniae Kp13 is a(More)
as well as the deletion of large parts of the mobA gene (including the mobB gene) and the tetracycline resistance gene tet(B). To the best of our knowledge, this is the first description of class 2-associated resistance gene cassettes in members of the genus Pasteurella. In contrast to P. multocida, which is found in the respiratory tract of various animal(More)
We read with great interest C. S. Antonio et al.’s letter describing the high prevalence of Acinetobacter baumannii carrying blaOXA-143 in Brazilian hospitals (1). Recently, we carried out a similar study, and although the blaOXA-143 gene was identified, its frequency was lower than that reported by Antonio et al. (1). During 2008, a total of 803(More)