Rena B. Kass

Learn More
PURPOSE The American Society of Breast Surgeons (ASBrS) sought to provide an evidence-based guideline on the use of neoadjuvant systemic therapy (NST) in the management of clinical stage II and III invasive breast cancer. METHODS A comprehensive nonsystematic review was performed of selected peer-reviewed literature published since 2000. The Education(More)
Breast tumor infiltrating lymphocytes (TIL) are enriched in tumor-specific cytotoxic T lymphocytes (CTL), and may represent a superior source of CTL compare to peripheral blood lymphocytes (PBL), for adoptive T cell immunotherapy of breast cancer. However, the immunocompetence of TIL and the possibility to consistently restore their tumor-specific lytic(More)
BACKGROUND Needle localization breast biopsy (NLBB) is the standard for removal of breast lesions after vacuum assisted core biopsy (VACB). Disadvantages include a miss rate of 0% to 22%, a positive margin rate of approximately 50%, and vasovagal reactions (approximately 20%). We hypothesized that clip migration after VACB is clinically significant and may(More)
BACKGROUND The number of women reaching top ranks in academic surgery is remarkably low. The purpose of this study was to identify: 1) barriers to becoming a female surgical leader; 2) key attributes that enable advancement and success; and 3) current leadership challenges faced as senior leaders. METHODS Semi-structured interviews of ten female surgical(More)
BACKGROUND This pilot study assessed the levels of patient emotional distress and impact on clinic throughput time. METHODS From April through August 2012, 149 breast cancer patients at the Penn State Hershey Breast Center were screened with the emotions thermometer (ET), a patient-rated visual 0-10 scale that measures distress, anxiety, depression,(More)
The American Society of Breast Surgeons (ASBrS) endorses the American Board of Internal Medicine's Choosing Wisely campaign statement: ''Don't routinely perform a double mastectomy in patients who have a single breast with cancer.'' 1 However, women with a newly diagnosed unilateral breast cancer are increasingly opting for bilateral mastectomy. This has(More)
OBJECTIVE To determine the identification of sentinel lymph node biopsy (SLNB) in breast cancer patients after intraoperative injection of unfiltered technetium-99m sulfur colloid (Tc-99) and blue dye. BACKGROUND SLNB guided by a combination of radioisotope and blue dye injection yields the best identification rates in breast cancer patients. Radioisotope(More)
BACKGROUND The purpose of this study was to assess national practices of surgeons who treat breast cancer in order to identify opportunities to improve patient education. METHODS In June 2012, the membership of the American Society of Breast Surgeons (ASBrS) (n = 2,818) was surveyed via email questionnaire to evaluate their current practice of shared(More)
The American Society of Breast Surgeons (ASBrS) encourages an evidence-based and patient value focused approach to contralateral prophylactic mastectomy (CPM). The ASBrS convened a panel of experts to develop a consensus statement on CPM. 1 The majority of women will obtain no oncologic benefit from CPM, and therefore CPM should be discouraged in(More)
We examined the effects of dietary vitamin E level on rat lung response to ozone (O3) inhalation. In one study, we fed 1-month-old Sprague-Dawley (SD) rats a test diet containing 0 or 50 IU vitamin E/kg for 2 months, and then exposed one-half of the animals from each dietary group to 0.8 ppm (1,568 micrograms/m3) O3 intermittently (8 hours daily) and the(More)