Ren-zhong Luo

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BACKGROUND Interleukin-37 (IL-37), a newly described member of IL-1family, functioned as a fundamental inhibitor of innate inflammatory and immune responses, especially its isoform IL-37b. OBJECTIVE This study was undertaken to evaluate the expression and regulation of IL-37b in children with allergic rhinitis (AR). METHODS Forty children with AR and(More)
OBJECTIVE To investigate the pathogenic bacteria distribution and drug susceptibility in children with acute otitis media (AOM) in different age and different season in the Pearl River Delta region. METHOD Four hundred and forty-two children diagnosed as AOM were divided into three groups by age factor and four groups by season factor. Midge ear pus(More)
INTRODUCTION Eosinophilic and noneosinophilic Nasal polyps (NPs) are different subtypes of NPs and require different treatment methods. OBJECTIVE To compare the histologic characteristics, mRNA and protein expression between Nasal Polyps with and without eosinophilia. METHODS NPs tissues were obtained from eighty-six NPs patients during surgery.(More)
OBJECTIVE To evaluate the clinical efficacy of sublingual immunotherapy (SLIT) with house-dust mite (HDM) extract and to examine the change of biomarkers (TIM-1, IL-5 and IL-10) after 6-month SLIT in children with allergic rhinitis (AR). METHODS One hundred and sixteen HDM-sensitized children with persistent AR were enrolled to assess the clinical(More)
OBJECTIVE To discuss the characteristics of auditory brainstem response in preterm very low birth weight (VLBW) babies and to investigate the correlations between the ABR and clinical characteristics. METHOD Fifty-nine VLBW babies (118 ears) were enrolled in the study and 30 term normal babies as the control group. Tympanometry, acoustic reflex, DPOAE,(More)
Background:Interleukin-31 (IL-31) is a recently described cytokine that is involved in helper T cell type-2 (Th2)-mediated diseases. However, its regulatory effect in the pathogenesis of children allergic rhinitis (AR) needs to be further characterized. This study sought to evaluate the expression and role of IL-31 in children with AR.Methods:Sixty children(More)
OBJECTIVE To study the characteristics of infants middle ear function of children (0-1 year old) with 226 Hz, 1000 Hz tympanometry. METHOD Tympanometric data using 226 Hz, 1 000 Hz probe tones were gained from 150 children (300 ears) aged 0-1 year old with a GSI tympstar middle ear analyzer. All of them were term birth, divided into 5 groups of 30(More)
OBJECTIVE To investigate the audiologic characteristics of the children with cleft lip and/or palate. METHOD Sixty-two children with cleft lip/palate were enrolled in the study. Tympanometry, DPOAE, ABR were tested in all the chidren. RESULT Regarding the ABR threshold as the diagnostic criteria, 51 (41.13%) ears had hearing loss, mainly moderate.(More)
OBJECTIVE To summarize the clinical manifestation, operative method and therapeutic effect of various type of laryngeal web in infants. METHODS The clinical data of 12 cases were analyzed, 5 cases of which were congenital laryngeal web (4 cases, glottic type; 1 case, subglottic type), 7 cases of which were secondary laryngeal web (1 case, tuberculous(More)
OBJECTIVE To elucidate the relationship between different cephalometric measurements and the severity of childhood OSAHS, then analyze the value of cephalometric measurements in predicting the severity of OSAHS in children. METHOD Sixty-one patients received PSG examination and standard lateral neck roentgenography including cervical trachea.(More)