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This study was conducted to compare the association of Gaussian and non-Gaussian magnetic resonance imaging (MRI)-derived parameters with histologic grade and MIB-1 (Ki-67 labeling) index (MI) in brain glioma. Sixty-five patients with pathologically confirmed glioma, who underwent diffusion-weighted MRI with 2 b values (0, 1000 s/mm2) and 22 b values (≤5000(More)
We have constructed 2 small interfering RNAs (siRNAs) specifically targeting homogenous 3D and 2B1 regions of 7 serotypes of the foot and mouth disease virus (FMDV) and tested the ability of siRNAs to inhibit virus replication in baby hamster kidney (BHK-21) cells and suckling mice. In this study, we generated transgenic mouse models integrating short(More)
By using bioinformatics computer programs, all foot-and-mouth disease virus (FMDV) genome sequences in public-domain databases were analyzed. Based on the results of homology analysis, 2 specific small interfering RNA (siRNA) targeting homogenous 3D and 2B1 regions of 7 serotypes of FMDV were prepared and 2 siRNA-expression vectors, pSi-FMD2 and pSi-FMD3,(More)
In contrast to the intensely studied genetic and epigenetic changes that induce host cell transformation to initiate tumor development, those that promote the malignant progression of cancer remain poorly defined. As emerging evidence suggests that the hypoxic tumor microenvironment could re-model the chromatin-associated proteome (chromatome) to induce(More)
We selected 42 early-stage primary biliary cirrhosis (PBC) patients and 30 healthy controls (HC). Metagenomic sequencing of the 16S rRNA gene was used to characterize the fecal microbiome. UPLC-MS/MS assaying of small molecules was used to characterize the metabolomes of the serum, urine and feces. Liquid chip assaying of serum cytokines was used to(More)
The aim of hybrid wind-solar-pumped -storage power system is to solve the electro-problem of remote and undeveloped areas short of power. Aim to the special physical geography condition of some island, hybrid wind-solar-pumped-storage power system is brought forward, which is based on traditional hybrid wind-solar power system, and which storages energy by(More)
In the present study, we report the whole genome sequences of two species, Ornithinibacillus contaminans DSM22953(T) isolated from human blood and Ornithinibacillus californiensis DSM 16628(T) isolated from marine sediment, in genus Ornithinibacillus. Comparative genomic study of the two species was conducted together with their close relative(More)
Collaborative filtering (CF) is a widely-used technique for generating personalized recommendations. CF systems are typically based on the ratings given by users to items. There are many factors influencing user's rating, beside user's interest and rating scale, item objective character is also the important element. Considering these factors, the improved(More)
In multiple grade proxy signature the signing right can be delegated from one grade to the next grade. In this paper, we first introduce a code-based multiple grade proxy signature based on Stern's identification scheme. The proposed scheme is the first code-based multiple grade proxy signature. Our scheme is secure on the syndrome decoding problem and(More)
This paper is to test the performance of Heat Pipe Fresh Air Ventilation, the core component of the Heat Pipe Fresh Air Ventilation this article designed is new energy-saving exchanger, namely the heat pipe heat exchanger, so the main tasks of measuring shift to a measurement of the heat pipe heat exchanger performance. To validate the design of a new heat(More)