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A metal-resistant and phosphate-solubilising bacterium, designated as strain D414T, was isolated from heavy metal (Pb, Cd, Cu and Zn)-polluted paddy soils at the surrounding area of Dabao Mountain Mine in Southeast China. The minimum inhibitory concentrations of heavy metals for strain D414T were 2000 mg L−1 (Cd), 800 mg L−1 (Pb), 150 mg L−1 (Cu) and 2500(More)
The aim of this study was to investigate signaling pathways for reversal of microRNA-127-mediated multi-drug resistance (MDR) in gliomas cells. Adriamycin-resistant glioma cell lines U251/adr and U87-MG/adr were established and we found that anti-microRNA-127 markedly reduced microRNA-127 expression levels in a time-dependent manner, leading to distinct(More)
MiR-184 was an important suppressor to tumor cells proliferation and invasion and some studies show that it was down-regulated in aggressive human tumor cells and a potential tumor therapy target through expression of miR-184 results in reduced tumor cell aggressiveness. In this study, miR-184 showed an inhibitive activity of glioma U87MG cell line and(More)
TGF-β/Smad2/3 signal pathway is regarded as a central regulator in various tumors, but its roles in brain cancer therapy remain unknown. In this study, we identify that the TGF-β/Smad2/3 signal pathway is activated in human brain glioma cells; inhibitor (SB203580) and siRNA against Smad2/3 quickly inhibited the phosphorylation of Smad2 and 3, expression of(More)
Iron plaques can prevent the uptake of heavy metals on the root surface of wetland plants. The Fe and Mn oxides produced by microorganisms are major Fe/Mn-oxidizing agents in the environment. This study is the first to investigate the influence of Fe/Mn-oxidizing bacteria on Fe/Mn plaque formation and the uptake of Cd and As on rice tissues. The oxide(More)
The two-stage least-squares inferential statistics (2SLS-IS) scripts in R provided here help to discriminate the quality of results in regression models, improving on prototypes by Dow (2007) and Eff and Dow (2009) that implemented a new two-stage least squares (2SLS) standard for regression models with missing data imputation and controls for(More)
A computational study using a hybrid DFT method (M06) on the cyclopropanation of endo-dicyclopentadiene with Simmons-Smith zinc carbenoids is reported. Each channel proceeds via the methylene-transfer mechanism with a reactant complex (RC) and subsquently a asynchronous transition state (TS). The channels with monomeric IZnCH(2)I attacking the double bonds(More)
BACKGROUND High-sensitivity C-reactive protein (hs-CRP) is an inflammatory marker that is associated with the outcomes of ischemic stroke. However, the role of hs-CRP levels in the functional outcomes after large-artery atherosclerosis (LAA) and small-artery occlusion (SAO) is poorly understood. METHODS We recruited 1299 patients diagnosed as having LAA(More)
A density functional theory (DFT) analysis was conducted on the hydrogenation of 2-alkyl-anthraquinone (AQ), including 2-ethyl-9,10-anthraquinone (eAQ) and 2-ethyl-5,6,7,8-tetrahydro-9,10-anthraquinone (H4 eAQ), to the corresponding anthrahydroquinone (AQH2 ) over a Pd6 H2 cluster. Hydrogenation of H4 eAQ is suggested to be more favorable than that of eAQ(More)
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