René Sander

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The value of sclerotherapy as prophylaxis against the first episode of variceal hemorrhage has not been established. Therefore, we randomly assigned 133 patients with cirrhosis of the liver (of alcoholic origin in 66 percent), esophageal varices, and no previous intestinal bleeding to either prophylactic sclerotherapy (n = 68) or no prophylaxis (n = 65).(More)
BACKGROUND There are very few data regarding sun exposure behaviour of patients with basal cell carcinoma (BCC) in central Europe. OBJECTIVES A case-control study of patients with sporadic BCC was conducted to assess the risk of occupational and leisure-time sun exposure behaviour, precursor lesions for skin cancer and phenotypic factors on the(More)
Between November, 1978 and July, 1985 36 recurrent broad-based villous adenomas in the gastrointestinal tract were treated with the Nd:YAG laser. Treatment was successful in 29 patients, who showed no recurrence within a period of six months or more. The average follow-up time was 16 months. Seven patients are still being treated. No serious complications(More)
BACKGROUND AND STUDY AIMS Sedation with propofol is associated with a high acceptance rate in upper gastrointestinal endoscopy. So far, however, there are no valid data on whether the use of propofol can increase the general quality of the endoscopic examination. PATIENTS AND METHODS A total of 60 patients referred for upper gastrointestinal endoscopy(More)
The combination of laser with endoluminal 192-iridium radiation for the palliation of malignancies of the oesophagus and the cardia has been introduced to overcome the short-lived effect of laser treatment alone. Concluding from early experience, this method seems to prolong the effect of laser treatment alone, with a low risk of complications. However the(More)
Gastrointestinal motility disorders are a commonly encountered problem. Although some are associated with organic alterations, others are defined by their symptoms, and no anatomic or histologic organic changes are to be found. In most cases, the etiology is completely unclear. Endoscopy, with the option of obtaining biopsies for histopathologic evaluation,(More)
Thirty-nine patients with malignant stenoses of the esophagus (22 adenocarcinomas, 17 squamous cell carcinomas) were treated either with Nd:YAG laser recanalization alone (N = 20) or with laser recanalization and subsequent endoluminal afterloading irradiation with iridium-192 at a dose of 3 x 7 Gy (6 x 7 Gy). Squamous cell carcinoma patients in the(More)
The Nd-YAG-laser is being used since ten years in gastroenterological endoscopy with good success. It can be used for treatment of bleeding lesions or lesions which potentially could bleed, for treatment of benign and malignant tumors, treatment of non-neoplastic stenoses and pathological changes in the region of the papilla. Own results with this treatment(More)