René Moutier

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This study examined the relationship among aggression towards lactating intruders, castration and brain GABA levels in three strains of mice (C57, C3H and CBA). Both C57 and C3H (but not CBA) animals showed reduced attack latencies following castration. C57 mice showed the highest intensity of this behavior and the response was almost absent in the CBA(More)
Two new esterase polymorphisms have been described in tissue homogenates of the four rat strains August/Orl, LEW/Orl, Long Evans/Orl, and WAG/Orl. Independent expression of these polymorphisms in the different strains and in various tissues of a particular animal agrees with the separate genetic control hypothesis; the gene symbols Es-4 and Es-5 have been(More)
Zygosity diagnosis has been performed in 79 pairs of twins using three methods. Simple sequence repeat length polymorphism (SSLP) analysis allows an efficient classification (MZ or DZ) with only a few markers following a simplified technique of extraction and amplification. A method based on a full questionnaire completed by parents about twin similarity(More)
Klaus Bender 1, M a r k Adams 2, Peter R. Baverstock 2, Maria den Bieman 3, Siegbert Bissbort 1, Rad im Brdi~ka 4, Geoffrey W. Butcher 5, Dona ld V. Cramer 6, Otto yon Deimling 7, Michael F .W. Festing 8, Eberhard Gtinther 9, Rona ld D. G u t t m a n n 1°, Hans J. Hedrich 11, Philip B. Kendall 12, Reinhard Kluge i t , Ren6 Moutier 13, Babette Simon 7, James(More)
In the rat, the autosomal recessive toothless (t1) mutation exhibits an acute form of osteopetrosis. This gene is not an allele of either ia or op that causes respectively, a transitory and acute form of the disease. Comparative radiographic study of t1/t1 and op/op mutants reveals some differences in respect to the size and shape of long bones. In contrast(More)
Two lethal mutations have been described in the rat: "osteopetrosis" (op) and "toothless" (tl). The op mutant can be cured by normal bone marrow infusion, while the tl mutant cannot. We report here additional data with regard to the tl mutant. The bone disease of the tl rat as in the op rat is associated with a precocious thymic atrophy, but bone lesions(More)
Substrains of inbred C3H mice differ significantly in their genetic constitution with respect to biochemical markers, skin grafting, and skeletal variations. The presence of such discrepancies among substrains poses a problem when comparing conclusions based on experiments done in different substrains. Therefore, methods of controlling the genetic(More)