Rejane Fukushima

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BACKGROUND/AIMS There are still uncertainties regarding the use of whole and parotid ductal saliva as indicators of chronic exposure to fluoride. This study evaluated the effect of water fluoride concentration, age, gender, geographical area and localization (urban/rural) on fluoride concentrations in whole and ductal saliva. METHODS Subjects (n = 300)(More)
The aim of this study was to validate the use of fingernail fluoride concentrations at ages 2-7 years as predictors of the risk for developing dental fluorosis in the permanent dentition. Fifty-six children of both genders (10-15 years of age) had their incisors and premolars examined for dental fluorosis using the Thylstrup-Fejerskov index. Fingernail(More)
BACKGROUND The effects of pimobendan on left atrial pressure (LAP) in dogs with mitral valve disease (MR) have not been documented in a quantitative manner. OBJECTIVE The objective was to document and study the short-term effects of pimobendan on LAP and echocardiographic parameters in MR dogs. ANIMALS Eight healthy Beagle dogs weighing 10.0-14.7 kg (3(More)
BACKGROUND The effects of furosemide on left atrial pressure (LAP) in dogs with mitral regurgitation (MR) have not been documented in a quantitative manner and between different routes of administration. OBJECTIVE To document LAP and echocardiographic parameters in MR dogs administered furosemide IV or PO, in order to document changes in LAP after(More)
BACKGROUND Despite many epidemiological reports concerning the efficacy of angiotensin-converting enzyme (ACE) inhibitors in dogs with mitral regurgitation (MR), the hemodynamic effects of ACE inhibitor administration have not been fully evaluated. OBJECTIVES To document left atrial pressure (LAP) in dogs with MR administered ACE inhibitors, in order to(More)
BACKGROUND Mitral valve regurgitation (MR) causes increased left atrial pressure (LAP) and is associated with occurrence of clinical signs. It will be useful to understand diurnal variations of LAP for the management of MR. HYPOTHESIS Circulatory parameters and diurnal rhythm are linked to clinical signs in cardiac diseases. LAP also exhibits a diurnal(More)
OBJECTIVES The aims of the present study were to evaluate the fluoride (F) concentrations in whole, defatted and chocolate milks commercially available in Brazil and to estimate the daily F intake from these sources. MATERIAL AND METHODS F concentrations were determined for 23 brands of milks, after HMDS-facilitated diffusion, using a F ion-specific(More)
Nails have been suggested as suitable biomarkers of exposure to F, with the advantage of being easily obtained. The effect of water F concentration, age, gender, nail growth rate and geographical area on the F concentration in the fingernail and toenail clippings were evaluated. Volunteers (n = 300) aged 3-7, 14-20, 30-40 and 50-60 years from five Brazilian(More)
The hearts of seven elderly dogs in which bradycardia-tachycardia syndrome (BTS) had been diagnosed electrocardiographically were examined post mortem. The clinical basis of the underlying heart disease was invariably mitral or mitral and tricuspid regurgitation. Microscopical examination of the sinoatrial (SA) node and the SA junctional region consistently(More)
A 3-year-old, 5 kg, male Toy Poodle with a mast cell tumor on the left pelvic limb was referred to Tokyo University of Agriculture and Technology Animal Hospital for an oncologic evaluation. On physical examination, a continuous bruit was auscultated over the left inguinal region with a palpable thrill. Cardiac auscultation identified a grade II/VI systolic(More)