Reiner Porschen

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Reutilization of thymidine (TdR) and 5-iodo-2'-deoxyuridine (I-UdR) released by dying tumour cells was assayed in the syngeneic adenocarcinoma EO 771 by injecting heat killed, labelled tumour cells into tumours. 3H and 125I liberation from labelled breakdown products was measured in tumours of various sizes without or with separation of tumours into viable(More)
Using a tracer technique, loss of cells from perivascular and average tumor cells of the syngeneic mammary adenocarcinoma EO 771 in male C57Bl/6J mice may be measured in the living animal, by the use of 125-labelled 5-iodo-2'-deoxyuridine (125I-UdR). It was the purpose of this paper to compare measurements in vivo with those made in vitro following local(More)
Introduction: High benign biliary stenoses, which can occur as a complication of disease or surgery, may be difficult to correct by open surgery and may also carry a high risk. An alternative to surgery is the percutaneous implantation of a flexible metallic stent or silicon prosthesis at the affected site. Methods: Twelve patients with benign biliary(More)
PURPOSE Radiotherapy, especially in the abdominal region, is frequently associated with gastrointestinal side effects. METHODS The article reviews the current knowledge about pathophysiological background, clinical symptoms and the treatment strategies of the major gastrointestinal side effects. RESULTS Several basics are investigated and depending on(More)
(17-123I)-Iodoheptadecanoic acid ([123I]HA) was used for dynamic planar scintigraphy of the liver in normal individuals (control I), in patients without liver disease but with elevated serum cholesterol and/or triglycerides (control II), and in patient groups with alcohol-induced fatty liver (PG I), fatty liver not due to alcohol (PG II), alcohol-induced(More)
Die aktuelle S3-Leitlinie stellt die Empfehlungen zur Diagnostik und Therapie der Plattenepithelkarzinome und Adenokarzinome des Ösophagus basierend auf Literaturevidenz und interdisziplinärem Expertenkonsens dar. Die Ösophagogastroskopie mit Biopsie, die Endosonographie und die Computertomographie von Hals, Thorax und Abdomen sind entscheidend für das(More)
Loss of cells from vital and necrotic areas of the syngeneic mammary adenocarcinoma EO 771 in male C57 BL/6J mice may be measured by use of 125I-labelled 5-iodo-2'-deoxyuridine (125I-UdR). Later than 50 hr after an intraperitoneal injection of 20 muCi 125I-UdR the incorporated activity of the entire tumour was externally measured and found to decrease with(More)
Berichtet wird der Fall eines CREST-Syndroms mit ausgeprägten Teleangiektasien im Bereich der Akren und des Gastrointestinaltraktes mit chronischen intestinalen Sickerblutungen und chronischer Blutungsanämie. Diese Teleangiektasien konnten eindeutig auf das CREST-Syndrom zurückgeführt werden, eine Eisensubstitution ist z.Z. bei dem Patienten ausreichend.(More)
The toxicity of 5-iodo-2'-deoxyuridine (I-UdR) was assayed in male C57 BL/6J mice bearing the syngeneic mammary adenocarcinoma EO 771 by injecting different doses of 'cold' I-UdR or 125-iodine labelled I-UdR. Host survival, tumour growth, DNA-precursor incorporation, whole-body retention and tumour activity loss rates were chosen as biological end points.(More)
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