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Associative learning during Pavlovian eyeblink conditioning has been shown to be regulated by 5-HT2A receptors. The existence of inverse agonists that retard learning through an action at the 5-HT2A receptor suggests the existence of constitutive activity at that receptor and that depletion of serotonin should have minimal effects on learning. We examined(More)
Associative learning during classical trace eyeblink conditioning has been shown to be regulated by serotonin 5-HT2A receptors and to be critically dependent on the integrity of frontal cortex. Chronic administration of 5-HT2A ligands has been shown to produce a selective up- or down-regulation of 5-HT2A receptors in frontal cortex. We examined whether(More)
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