Regine Unkels

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BACKGROUND Annually, 2.6 million stillbirths occur worldwide, 98% in developing countries. It is crucial that we understand causes and contributing factors. METHODS We conducted a systematic review of studies reporting factors associated with and cause(s) of stillbirth in low- and middle-income countries (2000-13). Narrative synthesis to compare(More)
OBJECTIVE To investigate the efficacy of a single prophylactic dose of ampicillin combined with metronidazole to prevent postcesarean section infections compared with a multiple day regimen in low-resource settings. DESIGN An evaluator-blinded randomized, controlled, noninferiority trial. SETTING Two rural hospitals in Tanzania. POPULATION Of 181(More)
A pregnancy after Mustard repair for transposition of the great arteries and ventricular septal defect with pulmonary stenosis is reported. The 23-year-old gravida 1 was treated with ACE inhibitors up to 26 weeks of gestation until cardiac medication was changed to dihydralazine. At 28 weeks of gestation the patient developed cardiac decompensation leading(More)
OBJECTIVE To compare methodology used to assign cause of and factors contributing to maternal death. DESIGN Reproductive Age Mortality Study. SETTING Malawi. POPULATION Maternal deaths among women of reproductive age. METHODS We compared cause of death as assigned by a facility-based maternal death review team, an expert panel using the(More)
BACKGROUND Community health workers (CHWs) can play vital roles in increasing coverage of basic health services. However, there is a need for a systematic categorisation of CHWs that will aid common understanding among policy makers, programme planners, and researchers. OBJECTIVE To identify the common themes in the definitions and descriptions of CHWs(More)
Urapidil is an antagonist of postsynaptic alpha 1 receptors, which leads to a diminution of the increased blood pressure by reducing the peripheral vascular resistance. With this pilot study we examined, whether it is possible to reduce the pregnancy-induced-hypertension with urapidil postpartum. The postpartum dosage of dihydralazine was diminished step by(More)
Laut Armutsbericht der Bundesrepublik Deutschland nehmen Kinder- und Familienarmut kontinuierlich zu. Viele der einzelnen Indikatoren für soziale Benachteiligung haben einen negativen Einfluss auf den Verlauf von Schwangerschaft, Geburt und postpartaler Phase. Daher muss auch in Deutschland mit relevanten gesundheitlichen Problemen für Frauen und Kinder(More)
BACKGROUND Assessing the feasibility of conducting a prospective Reproductive Age Mortality Survey (RAMOS) study in the low-income setting of Mangochi District, Malawi to obtain cotemporaneous estimates of the number, cause of and conditions associated with maternal deaths (MD) in all women of reproductive age (WRA) (n = 207 688). METHODS MD among all(More)
BACKGROUND The three delays model proposes that maternal mortality is associated with delays in: 1) deciding to seek care; 2) reaching the healthcare facility; and 3) receiving care. Previously, the majority of women who died were reported to have experienced type 1 and 2 delays. With increased coverage of healthcare services, we sought to explore the(More)
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