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Stimulation of bone repair with ultrasound: a review of the possible mechanic effects.
In vivo and in vitro studies have demonstrated the positive role that ultrasound can play in the enhancement of fracture healing or in the reactivation of a failed healing process. We review theExpand
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Stimulation of Bone Repair with Ultrasound.
This chapter reviews the different options available for the use of ultrasound in the enhancement of fracture healing or in the reactivation of a failed healing process: LIPUS, shock waves andExpand
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An investigation of BMP-7 mediated alterations to BMP signalling components in human tenocyte-like cells
The incidence of tendon re-tears post-surgery is an ever present complication. It is suggested that the application of biological factors, such as bone morphogenetic protein 7 (BMP-7), can reduceExpand
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A Focused Low-Intensity Pulsed Ultrasound (FLIPUS) System for Cell Stimulation: Physical and Biological Proof of Principle
Quantitative ultrasound (QUS) is a promising technique for bone tissue evaluation. Highly focused transducers used for QUS also have the capability to be applied for tissue-regenerative purposes andExpand
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Activation of Mechanosensitive Transcription Factors in Murine C2C12 Mesenchymal Precursors by Focused Low-Intensity Pulsed Ultrasound (FLIPUS)
In this paper, we investigated the mechanoresponse of C2C12 mesenchymal precursor cells to focused low-intensity pulsed ultrasound (FLIPUS). The setup has been developed for in vitro stimulation ofExpand
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Influence of Donor Age and Stimulation Intensity on Osteogenic Differentiation of Rat Mesenchymal Stromal Cells in Response to Focused Low-Intensity Pulsed Ultrasound.
A focused low-intensity pulsed ultrasound (FLIPUS) was used to investigate the effects of stimulation period, acoustic intensity and donor age on the osteogenic differentiation potential of ratExpand
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Mechanosensitive response of murine C2C12 myoblasts to focused Low-Intensity Pulsed Ultrasound (FLIPUS) stimulation
Quantitative Ultrasound (QUS) is a promising technique for bone tissue evaluation. Highly focused transducers, used for QUS, have also a capability to be applied for tissue-regenerative purposes andExpand
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In-vitro stimulation of cells of the musculoskeletal system with focused Low-Intensity Pulsed Ultrasound (FLIPUS): Analyses of cellular activities in response to the optimized acoustic dose
Low-Intensity Pulsed Ultrasound (LIPUS) is a safe treatment for fresh fractures, delayed- and non-union bone. Certain inconsistency is associated with the reported in-vitro data, which could beExpand
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Functional regulation of YAP mechanosensitive transcriptional coactivator by Focused Low-Intensity Pulsed Ultrasound (FLIPUS) enhances proliferation of murine mesenchymal precursors
Yes-associated protein (YAP) acts as a mechanotransducer in determining the cell fate of murine C2C12 mesenchymal precursors as investigated after stimulation with ultrasound. We applied FocusedExpand
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