Regina Cybulska

Learn More
Sublethal stress stimuli such as systemic endotoxin treatment can induce tolerance of the brain to subsequent ischemic stress, which results in a decreased infarct size. Based on this evidence, we hypothesized that lipopolysaccharide (LPS)-induced preconditioning could protect hippocampal neurons in epileptic rats. To test this hypothesis, the(More)
The present paper is the first work to determine the effect of lipopolysaccharide (LPS) in the pilocarpine model of epilepsy on the morphology of rat hippocampal astrocytes in vivo. The study involved adult male Wistar rats, which 72 hours prior to administration of pilocarpine hydrochloride (PILO) were intraperitoneally (ip) preconditioned with LPS at a(More)
AChE activity (EC in the pig brain was examined by spectrophotometric method and histochemically in the light and electron microscope. The results obtained correlate to a high degree with the existing data concerning the activity of the studied enzyme in other mammals. In the pig, the highest activity was encountered in the striatum nucleus(More)
Male Wistar rats were given phentolamine or phenoxybenzamine in the lateral ventricles in doses of 1 mg/kg. After 30 minutes they received in the same way atropine in doses of 1 mg/kg or carbachol in doses of 0.05 mg/kg. The control group was given physiological saline. The animals were decapitated 30 minutes after drug administration. The Falck and Hillarp(More)
The investigations were carried out on the corpus geniculatum laterale of the pig with the aim to differentiate the structure of its neurons on the basis of the antigenic properties of the nervous tissue. The antigenic material consisted of the homogenate of the corpus geniculatum laterale (H) and of its nuclear (P1) and mitochondrial (P2) fractions. The(More)
Wistar rats were given phentolamine into the ventriculus lateralis. The D1 group of rats received a larger dose than the D2 group. The animals were decapitated within 2 hours after phentolamine injection. The FALCK fluorescence technique was applied to demonstrate the fluorescence of catecholaminergic structures. The results in rat brain areas selected(More)
The experiment was carried out on rabbit females of New Zealand breed weighing about 3 kg. The animals from the experimental group received. Cladribine in the dose of 0.1 mg/kg for 7 days. Specimens of retina were collected for ultrastructural examinations. It was revealed that administration of Cladribine in the dose corresponding to the therapeutic dose(More)
The aim of the paper was to trace the haloperidol effect in the acute and chronic experiments on the histofluorescence in the caudate nucleus of the rat and in conditions of pretreatment of those animals with agonistic and antagonistic compounds of acetylcholine. The experiments were performed on 35 Wistar rats of 180 g mean body weight. According to the(More)