Regina Aparecida Garcia de Lima

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We have used anatomical methods and whole-cell patch-clamp recording to assess the distribution of nicotinic receptors in the tectum of Xenopus frogs and to measure effects of nicotinic ligands (carbachol, cytisine and nicotine) on glutamatergic spontaneous miniature excitatory postsynaptic currents. Our results confirm that retinotectal axons account for(More)
The effect of Cyclosporin A on nitric oxide production was studied in cultured LLC- PK1 cells. For this purpose the cells were incubated with vehicle (olive oil, 10 microg/ml in DMSO), Cyclosporin A (CsA, 10 microg/ml), tumor necrosis factor (TNF-alpha, 150 U/ml) + interferon (IFN-gamma, 500 U/ml) to upregulate NOS synthesis, and therefore NO production(More)
Late effects of cancer treatment in children, adolescents and young adults may be physical, social, and emotional, with effects on their quality of life. Through an ethnographic study, we sought to identify the impact on survivors' quality of life caused by late effects of treatment of childhood cancer. Twenty-one survivors participated in the study with(More)
Cancer-related fatigue (CRF) is the most stressful and prevalent symptom in paediatric oncology patients. This integrative review aimed to identify, analyse and synthesise the evidence of non-pharmacological intervention studies to manage fatigue and psychological stress in a paediatric population with cancer. Eight electronic databases were used for the(More)
The use of puppets is an effective strategy for promoting children to express thoughts and feelings about daily experiences. However, very little information is available about its use in children with type 1 diabetes mellitus. The procedures for using puppets during qualitative interviews in children with Type 1 diabetes mellitus were described, which(More)
PURPOSE To describe Brazilian mothers' experiences of home care for their low birth weight (LBW) infants. DESIGN Descriptive. SAMPLE Eleven Brazilian mothers whose LBW infants were hospitalized at birth and followed up for a period of four weeks. MAIN OUTCOME VARIABLE Brazilian mothers' recollections about the home care of their infants. RESULTS The(More)
Living with a chronic condition is difficult at any stage of life, especially when considering HIV/AIDS, a stigmatized condition that elicits so much discrimination and which may become an aggravating factor when it occurs during adolescence. This study aimed to understand the experience of adolescents with HIV/AIDS concerning medication adherence. This is(More)
In the light of the multiple dimensions involving the phenomenon of pain in children and adolescents with cancer, this study aimed to present a reflection on interdisciplinary practice as a healthcare resource for these patients. The study focused on the aspects related to the need for this practice in the aforementioned context and the challenges of its(More)
This study aims to understand the experience of adolescents with cancer, family and the health team regarding death in the healthcare context, in the light of Edgar Morin's proposed theoretical framework of complexity. Participants were 12 adolescents, 14 relatives and 25 health professionals. The interview was used for data collection. The discussion of(More)
Cystic Fibrosis is a chronic disease with an extensive impact on family life. The experience of disease is the manner how individuals respond to the disease, assigning meaning meanings and searching for ways to deal with it in their daily lives. The objective of this study was to understand the experience of Cystic Fibrosis in the family context. This is an(More)