Rebecca Kuenzler

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OBJECTIVE To assess the safety, tolerability, and preliminary efficacy of NP001, a novel immune regulator of inflammatory monocytes/macrophages, for slowing progression of amyotrophic lateral sclerosis (ALS). METHODS This was a phase 2 randomized, double-blind, placebo-controlled trial of NP001 in 136 patients with ALS of <3 years' duration and forced(More)
Multielectrode catheters provide a percutaneous means of recording activation near the epicardium but only for a relatively small number of sites that are restricted to the major coronary vessels. We have applied a statistical signal processing technique to estimate the value of activation time over the entire epicardium (490 sites) from leadsets consisting(More)
AIM This prospective study was performed as a Phase 1 Food and Drug Administration clinical trial to assess the safety and feasibility of robotically assisted coronary artery bypass grafting (CABG). METHODS Eighteen patients undergoing elective CABG were enrolled in this study. Full sternotomy was performed in 17 of 18 patients, while cardiopulmonary(More)
Background: Here we explore a method of using robotics to reduce morbidity and mortality in conventional coronary surgery. Methods: Using a robotic surgical system two surgeons completed five steps: (1) 80 synthetic suture exercises; (2) 76 left internal thoracic artery to left anterior descending (LIMA-to-LAD) on porcine hearts; (3) cadaveric port(More)
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