Rebecca Kimball

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We previously showed (5) that in double animals of Euplotes the two separate macronuclei begin D N A synthesis simultaneously, demonstrating that the cytoplasm plays a role in initiating DNA synthesis. By studying the timing of DNA synthesis in both the micronucleus and the macronucleus, we have obtained evidence that the initiation of D N A synthesis(More)
I Goldberg, L., E. Klein, and G. Klein, Exptl. Cell Research, 1, 543 (1950). 10 Coddington, A., unpublished results. 11 Klenow, H., and R. Emberland; Arch. Biochem. Biophys., 58, 276 (1955). 12 Price, V. E., M. C. Otey, and P. Plesner in Methods in Enzymology, eds. S. P. Colowick and N. 0. Kaplan (New York: Academic Press, 1955), vol. 2, p. 448. 13 Kalckar,(More)
Mammalian target of rapamycin (mTOR) is a protein that regulates cell growth in response to altered nutrient and growth factor availability. Our objective was to assess activated mTOR and its intracellular intermediates p70, and 4EBP1 in placental and invasive trophoblast cells in a hypoxia-induced model of intrauterine growth restriction (IUGR) in rats.(More)
Haemophilus influenzae is shown to lack the inducible, error-free repair system for alkylation damage that others have found in Escherichia coli. Prior growth in a low concentration of N-methyl-N'-nitro-N-nitrosoguanidine had only an additive effect on a subsequent brief exposure to a high concentration. Furthermore, chloramphenicol did not significantly(More)