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A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
TLDR
The results support the hypothesis that rare coding variants can pinpoint causal genes within known genetic loci and illustrate that applying the approach systematically to detect new loci requires extremely large sample sizes.
PEDIGREE ERROR DUE TO EXTRA‐PAIR REPRODUCTION SUBSTANTIALLY BIASES ESTIMATES OF INBREEDING DEPRESSION
TLDR
Paternity error caused widespread error in estimates of f and male reproductive success, causing inbreeding depression in male and female annual and lifetime reproductive success and juvenile male survival to be substantially underestimated and inbreeding depressed in adult male survival when paternity error was ignored.
EXTRA‐PAIR PATERNITY AND THE VARIANCE IN MALE FITNESS IN SONG SPARROWS (MELOSPIZA MELODIA)
TLDR
Although EPP altered individual males’ contributions to future generations, its impact on population‐level parameters such as the opportunity for selection and effective population size was limited.
Comprehensive paternity assignment: genotype, spatial location and social status in song sparrows, Melospiza Melodia
TLDR
These analyses demonstrate the integration of genetic and ecological information to achieve comprehensive paternity assignment and direct biological insight, illustrate the potential biases that common forms of incomplete sampling could have on estimated patterns of EPP, and provide an essential basis for understanding the evolutionary causes and consequences of E PP.
Additive Genetic Variance, Heritability, and Inbreeding Depression in Male Extra-Pair Reproductive Success
TLDR
The data suggest that females could accrue indirect genetic benefits, in terms of increased EPRS of outbred sons, by mating with unrelated social or extra-pair mates, in contrast to any indirect benefit of extra- Pair reproduction in Terms of producing sons with high additive genetic value for E PRS is most likely to be small.
Sex-specific differential survival of extra-pair and within-pair offspring in song sparrows, Melospiza melodia
TLDR
Data from free-living song sparrows indicate that extra-pair paternity may impose an indirect cost on females via their female offspring and that sex-specific genetic, environmental or maternal effects may shape extra- Pair reproduction.
Female mating preferences and offspring survival: testing hypotheses on the genetic basis of mate choice in a wild lekking bird
TLDR
Testing whether offspring survival correlated with patterns of mate choice on lekking lance‐tailed manakins found selection on mate choice for heterozygosity appeared stronger than that for relatedness and may be the primary mechanism maintaining genetic variation in this system despite directional sexual selection.
Disentangling the effect of genes, the environment and chance on sex ratio variation in a wild bird population
TLDR
It is concluded that female song sparrows do not, and perhaps cannot, adjust the sex of their offspring, and the sex ratio variation observed matches that expected under random Mendelian segregation.
Inbreeding coefficient and heterozygosity–fitness correlations in unhatched and hatched song sparrow nestmates
TLDR
Relationships between pedigree‐based estimates of f, multilocus heterozygosity (MLH) and the probability of survival to hatch in song sparrow nestmates were examined and f and MLH were weakly, but significantly negatively correlated.
Heritability of female extra-pair paternity rate in song sparrows (Melospiza melodia)
TLDR
The force of selection on extra-pair reproduction through indirect additive genetic benefits may be relatively weak, but the additive genetic variance and non-zero heritability observed in female EPP rate allow for multiple further genetic mechanisms to drive and constrain mating system evolution.
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