This report analyses the past decade of UK evidence to explore the relationship between housing circumstances and the experience of poverty. It considers the relative importance of housing cost, quality and location in the impact of poverty on people's lives, and the role of housing in enabling people to increase their income from work. Over the past two… (More)
BACKGROUND Dietary fatty acids may be important in regulating gene expression. However, little is known about the effect of changes in dietary fatty acids on gene regulation in human skeletal muscle. OBJECTIVE The objective was to determine the effect of altered dietary fat intake on the expression of genes encoding proteins necessary for fatty acid… (More)
Fasting forces adaptive changes in whole body and skeletal muscle metabolism that increase fat oxidation and decrease the oxidation of carbohydrate. We tested the hypothesis that 40 h of fasting would decrease pyruvate dehydrogenase (PDH) activity and increase PDH kinase (PDK) isoform mRNA expression in human skeletal muscle. The putative transcriptional… (More)
The Centre for the Analysis of Social Exclusion (CASE) is a multidisciplinary research centre based at the London School of Economics and Political Science (LSE), within the Suntory and Toyota International Centres for Economics and Related Disciplines (STICERD). Our focus is on exploration of different dimensions of social disadvantage, particularly from… (More)
Coalition Ministers were highly critical of the state of UK housing when they took power. How far were they able to improve a system they had described as " dysfunctional " ? The Coalition reduced the extent of UK central government involvement in housing. But, in so doing, it lowered its ability to achieve its own housing policy goals, or tackle… (More)
Acknowledgements We would like to thank Alex Fenton for his work in developing and updating the UMBR indicator and worklessness series that we use in this paper; for their helpful comments on an earlier draft; and Cheryl Conner for her help with the paper's production. All errors and omissions are our own.
Anatomical atlases document safe corridors for placement of wires when using fine-wire circular external fixation. The furthest posterolateral corridor described in the distal tibia is through the fibula. This limits the crossing angle and stability of the frame. In this paper we describe a new, safe Retro-Fibular Wire corridor, which provides greater… (More)
Provoked by concerns that mono-tenure areas were increasingly associated with mono-social group areas, social problems, and lack of choice in the housing market, the promotion of 'tenure diversification' and 'mixed tenure' within local areas (of indeterminate size) has been an important element of housing policy since the 1980s. Policy instruments at least… (More)