Rebecca F. Wang

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Dsk5 mice have a gain of function in the epidermal growth factor receptor (EGFR), caused by a point mutation in the kinase domain. We analyzed the effect of this mutation on liver size, histology, and composition. We found that the livers of 12-wk-old male Dsk5 heterozygotes (+/Dsk5) were 62% heavier compared with those of wild-type controls (+/+). The(More)
29 Dsk5 mice have a gain-of-function in the epidermal growth factor receptor (EGFR), caused by a point 30 mutation in the kinase domain. We analyzed the effect of this mutation on liver size, histology, and 31 composition. We found that the livers of 12-week old male Dsk5 heterozygotes (+/Dsk5) were 62% 32 heavier compared to those of wild-type controls(More)
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