Rebecca Ellis

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Several lines of reasoning suggest that the phosphorylated axonal form of the neurofilament subunit NF-H is likely to be released from damaged and diseased neurons in significant amounts. Detection of this protein in serum or CSF might therefore provide information about the presence and degree of neuronal loss. We therefore developed a sensitive NF-H ELISA(More)
We provide the first data that cathepsin B (Cath B), a lysosomal cysteine protease, is up-regulated following contusion-spinal cord injury (SCI). Following T12 laminectomy and moderate contusion, Cath B mRNA and protein expression profiles were examined from 2 to 168 h post-injury in rats using real-time PCR and immunoblots, respectively. Contusion injury(More)
Mechanical spinal cord injury (SCI) initiates a cascade of pathochemical and pathophysiological events, collectively known as the secondary injury. There has been a long-standing interest in understanding the activation and involvement of proteases in this secondary injury process. Several proteases including the calpains, caspases and matrix(More)
Int J Exerc Sci 2(3) : 202-214, 2009. The purpose of this study was to utilize the disablement pathway model to examine the contribution of physical function, dyspnea, and pain to disability in activities-of-daily-living (ADL) in culturally diverse older adults. Participants were 51 older adults (age = 69.0 years ± 9.7; 76.5% African-American, 51.0% < high(More)
BACKGROUND Given the importance of physical activity (PA) and the low activity levels among adults with physical disabilities, it is important to understand how temporal changes in psychosocial constructs affect PA changes over time. OBJECTIVE/HYPOTHESIS Examine if changes in the transtheoretical model (TTM) constructs affected changes in PA levels over(More)
The purpose of this study was to determine if electronic messaging would increase min of aerobic physical activity (PA) among older adults. Participants were active older adults (n = 28; M age = 60 years, SD = 5.99, and range = 51-74 years). Using an incomplete within-subjects crossover design, participants were randomly assigned to begin the 4-week study(More)
The Dissertation Advisory Committee and the student's Department Chair, as representatives of the faculty, certify that this dissertation has met all standards of excellence and scholarship as determined by the faculty. The Dean of the College of Education concurs. By presenting this dissertation as a partial fulfillment of the requirements for the advanced(More)
#Patchworks is a citizen-led co-design project to design innovative technologies for and with homeless people in the North West of England. The project involved 3 quite distinct communities: Signposts, a community resource centre that works with homeless people in Morecambe; Madlab, a community of DIY hackers and creative technologists in Manchester; and an(More)
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