Rebecca A. Krey

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We studied preBötzinger Complex (preBötC) inspiratory interneurons to determine the cellular mechanisms that influence burst termination in a mammalian central pattern generator. Neonatal mouse slice preparations that retain preBötC neurons generate respiratory motor rhythms in vitro. Inspiratory-related bursts rely on inward currents that flux Na(+), thus(More)
We examined the neural bases of inspiratory bursts in the preBötzinger Complex (preBötC) in slice preparations of neonatal mice that retain respiratory network functions in vitro. It is well established that inward currents including persistent Na current (INaP) and Ca activated nonspecific cation current (ICAN) initiate and maintain inspiratory bursts, but(More)
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