Razvan I. Arsenescu

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Polychlorinated Biphenyl-77 Induces Adipocyte Differentiation and Proinflammatory Adipokines and Promotes Obesity and Atherosclerosis

Violeta Arsenescu, Razvan I. Arsenescu, Victoria L. King, Hollie I. Swanson, Lisa A. Cassis
Environmental health perspectives
2008

BACKGROUND Obesity, an inflammatory condition linked to cardiovascular disease, is associated with expansion of adipose tissue. Highly prevalent coplanar polychlorinated biphenyls (PCBs) such as… (More)

IL-12 induction of mRNA encoding substance P in murine macrophages from the spleen and sites of inflammation.

Razvan I. Arsenescu, Arthur Blum, Ahmed Metwali, David E. Elliott, Joel V. Weinstock
Journal of immunology
2005

Substance P (SP), a neuropeptide, interacts with the neurokinin 1 receptor (NK-1R) on immune cells to help control IFN-gamma production. In murine schistosomiasis mansoni, schistosome worms produce… (More)

Molecular Signaling and Dysfunction of the Human Reactive Enteric Glial Cell Phenotype: Implications for GI Infection, IBD, POI, Neurological, Motility, and GI Disorders.

Andrómeda Liñán-Rico, Fabio Turco, +9 authors Fievos L Christofi
Inflammatory bowel diseases
2016

BACKGROUND Clinical observations or animal studies implicate enteric glial cells in motility disorders, irritable bowel syndrome, inflammatory bowel disease, gastrointestinal (GI) infections,… (More)

Measurement of Charged Particle Production from 450 GeV / c Protons on Beryllium . The NA 56 / SPY Collaboration

Giovanna Ambrosini, Razvan I. Arsenescu, +38 authors Marv Weber
1999

This paper presents the results on charged particle yields and production ratios as measured by the NA56/SPY experiment for 450 GeV/c proton interactions on beryllium targets. The data cover a… (More)

Adipose Tissue Immune Response: Novel Triggers and Consequences for Chronic Inflammatory Conditions

Giorgio Ghigliotti, Chiara Barisione, +9 authors Violeta Arsenescu
Inflammation
2014

Adipose tissue inflammation mediates the association between excessive body fat accumulation and several chronic inflammatory diseases. A high prevalence of obesity-associated adipose tissue… (More)

Signature biomarkers in Crohn's disease: toward a molecular classification

Razvan I. Arsenescu, Maria E. C. Bruno, +6 authors Charlotte Slayton Kaetzel
Mucosal Immunology
2008

In an effort to develop a molecular classification scheme for Crohn's disease (CD), mucosal biopsies from 69 CD patients and 28 normal controls were analyzed for expression of the RelA subunit of… (More)

IL-18 and IL-12 signal through the NF-kappa B pathway to induce NK-1R expression on T cells.

Joel V. Weinstock, Arthur Blum, Ahmed Metwali, David E. Elliott, Razvan I. Arsenescu
Journal of immunology
2003

Substance P engages the T cell neurokinin 1 receptor (NK-1R) to enhance IFN-gamma production. NK-1R on T cells is inducible. We studied mechanisms regulating T cell NK-1R expression. Murine… (More)

Larazotide acetate in patients with coeliac disease undergoing a gluten challenge: a randomised placebo-controlled study.

Ciaran Kelly, Peter H. R. Green, +10 authors Richard N Fedorak
Alimentary pharmacology & therapeutics
2013

BACKGROUND Coeliac disease, an autoimmune disorder triggered by gluten ingestion, is managed by a gluten-free diet (GFD), which is difficult for many patients. Larazotide acetate is a first-in-class… (More)

Intestinal Epithelial Serum Amyloid A Modulates Bacterial Growth In Vitro and Pro-Inflammatory Responses in Mouse Experimental Colitis

Erik R. M. Eckhardt, Jassir Witta, +7 authors Willem J. S. de Villiers
BMC gastroenterology
2010

BACKGROUND Serum Amyloid A (SAA) is a major acute phase protein of unknown function. SAA is mostly expressed in the liver, but also in other tissues including the intestinal epithelium. SAA… (More)

Use of probe-based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence.

Kenneth K. Wang, David L. Carr-Locke, +23 authors Alvin M. Zfass
United European gastroenterology journal
2015

BACKGROUND Probe-based confocal laser endomicroscopy (pCLE) provides microscopic imaging during an endoscopic procedure. Its introduction as a standard modality in gastroenterology has brought… (More)

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