Learn More
BACKGROUND Some current pacing systems can automatically detect and record atrial tachyarrhythmias that may be asymptomatic. We prospectively studied a 312-patient (pt) subgroup of MOST (MOde Selection Trial), a 2010-patient, 6-year randomized trial of DDDR versus VVIR pacing in sinus node dysfunction (SND). The purpose of the study was to correlate atrial(More)
OBJECTIVE To evaluate quantitative measures of eye movements as possible biomarkers in prediagnostic and early stages of Huntington disease (HD). METHODS The study sample (n = 215) included individuals both at risk and recently diagnosed with HD. All participants completed a uniform clinical evaluation which included administration of the Unified(More)
BACKGROUND Establishing a diagnosis in patients with unexplained syncope is complicated by infrequent and unpredictable events. Prolonged monitoring may be an alternative strategy to conventional testing with short-term monitoring and provocative tilt and electrophysiological testing. METHODS AND RESULTS Sixty patients (aged 66+/-14 years, 33 male) with(More)
As Wikipedia has become an indispensable source of online information, concerns about who writes, edits, and maintains it have come to the forefront. In particular, the 2010 UNU-MERIT survey found evidence of a significant gender skew: fewer than 13% of Wikipedia contributors are women. However, the number of contributors is just one way to examine gender(More)
A transvenous lead system for implantable defibrillators would obviate a surgical thoracotomy and reduce the morbidity and mortality associated with implantation. We evaluated the clinical performance of a new nonthoracotomy lead system that included a defibrillation lead in the coronary sinus. At the time of defibrillator implantation, transvenous(More)
Research libraries hold vast and increasing amounts of high-quality digital content. Such content includes not just bibliographic records and born-digital materials, but also digital versions of the library's primary holdings such as archival manuscripts and pictorial collections. Libraries have traditionally provided access to their materials through(More)
BACKGROUND This study tested the hypothesis that rate-adaptive atrial pacing would prevent paroxysmal atrial fibrillation (PAF) in patients with frequent PAF in the absence of symptomatic bradycardia. METHODS AND RESULTS Patients (n=97) with antiarrhythmic drug-refractory PAF received a Medtronic Thera DR pacemaker 3 months before planned AV node(More)
One of the main goals of the Recovery.gov Web site is to provide information about how funds for the American Recovery and Reinvestment Act (ARRA) of 2009 are allocated and spent. In this report, we propose a reporting architecture that would focus on the reporting services rather than the Web site and page design, and that uses these Web services to build(More)
The prognostic value of electrophysiology testing was studied in 75 asymptomatic patients with the Wolff-Parkinson-White electrocardiographic pattern. All patients underwent electrophysiology testing at entry to the study and were followed up annually for a total of 348 patient-years (median, 4.3 years). There were 44 male and 31 female patients, and age at(More)
BACKGROUND Syncope in patients with supraventricular tachycardia has been suggested to be an ominous finding, predictive of rapid rates during tachycardia. METHODS AND RESULTS To explore the mechanism of syncope during supraventricular tachycardia, tachycardia was induced in the supine position and after passive head-up tilting to 60 degrees in 13(More)