Raymond Wai-Hung Yung

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BACKGROUND An outbreak of severe acute respiratory syndrome (SARS) has been reported in Hong Kong. We investigated the viral cause and clinical presentation among 50 patients. METHODS We analysed case notes and microbiological findings for 50 patients with SARS, representing more than five separate epidemiologically linked transmission clusters. We(More)
BACKGROUND Few data are available about the effectiveness of nonpharmaceutical interventions for preventing influenza virus transmission. OBJECTIVE To investigate whether hand hygiene and use of facemasks prevents household transmission of influenza. DESIGN Cluster randomized, controlled trial. Randomization was computer generated; allocation was(More)
BACKGROUND There are sparse data on whether non-pharmaceutical interventions can reduce the spread of influenza. We implemented a study of the feasibility and efficacy of face masks and hand hygiene to reduce influenza transmission among Hong Kong household members. METHODOLOGY/PRINCIPAL FINDINGS We conducted a cluster randomized controlled trial of(More)
BACKGROUND Laribacter hongkongensis has been recovered from several patients with gastroenteritis. However, the causative role of this organism in human gastroenteritis is still unproven, and sources of the bacterium are unknown. We undertook a multicentre case-control study to investigate the association of L hongkongensis with gastroenteritis. METHODS(More)
A series of 31 patients with probable SARS, diagnosed from WHO criteria, were treated according to a treatment protocol consisting of antibacterials and a combination of ribavirin and methylprednisolone. Through experience with the first 11 patients, we were able to finalise standard dose regimens, including pulsed methylprednisolone. One patient recovered(More)
We did a case-control study in five Hong Kong hospitals, with 241 non-infected and 13 infected staff with documented exposures to 11 index patients with severe acute respiratory syndrome (SARS) during patient care. All participants were surveyed about use of mask, gloves, gowns, and hand-washing, as recommended under droplets and contact precautions when(More)
BACKGROUND Recently, we described the discovery of a novel group 2 coronavirus, coronavirus HKU1 (CoV-HKU1), from a patient with pneumonia. However, the clinical and molecular epidemiological features of CoV-HKU1-associated pneumonia are unknown. METHODS Prospectively collected (during a 12-month period) nasopharyngeal aspirates (NPAs) from patients with(More)
OBJECTIVE To describe the epidemiology, clinical and laboratory findings, and outcomes of patients presenting locally with dengue. DESIGN Retrospective review of case records. SETTING Public hospitals, Hong Kong. PATIENTS Medical records of all laboratory-confirmed dengue patients admitted to public hospitals during 1998 to 2005 were reviewed(More)
The MICs of 13 antimicrobial agents including seven fluoroquinolones (ciprofloxacin, levofloxacin, sparfloxacin, grepafloxacin, gatifloxacin, moxifloxacin and clinafloxacin) for Streptococcus pneumoniae isolates obtained from all regions of Hong Kong in the year 2000 were determined by the Etest. Overall, 39.4% of 180 isolates were susceptible to(More)
1. Graves MH, Janda MJ. Rat-bite fever (Streptobacillus moniliformis): a potential emerging disease. Int J Infect Dis. 2001;5: 151–4. 2. Morse SS. Factors in the emergence of infectious disease. Emerg Infect Dis. 1995;1:7–15. 3. Freels LK, Elliott SP. Rat bite fever: three case reports and a literature review. Clin Pediatr (Phila). 2004;43:291–5. 4. Salmon(More)