Raymond S. Crawford

Learn More
Single-chain Fv (scFv) molecules exhibit highly specific tumour-targeting properties in tumour-bearing mice. However, because of their smaller size and monovalent binding, the quantities of radiolabelled scFv retained in tumours limit their therapeutic applications. Diabodies are dimeric antibody-based molecules composed of two non-covalently associated(More)
Oxidized low density lipoprotein (LDL) promotes atherogenesis. Although pharmacological antioxidants such as probucol inhibit both LDL oxidation and atherosclerosis in hyperlipidemic animals, the effects of natural antioxidants such as vitamin E are inconclusive. To further determine the effects of supplemental dietary antioxidants in vivo, we evaluated(More)
The use of archived injormatiori arid knowledge derived from data-driven system, both at the poirit of care and retrospectively, is critical to iniproving the balance between healthcare e.rperiditure arid healthcare qirality. Data-driveti clinical decision support, augmented by pe$orinance feedback arid edircatiori, is a logical addition to consensus arid(More)
  • 1