Raymond S. Crawford

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Oxidized low density lipoprotein (LDL) promotes atherogenesis. Although pharmacological antioxidants such as probucol inhibit both LDL oxidation and atherosclerosis in hyperlipidemic animals, the effects of natural antioxidants such as vitamin E are inconclusive. To further determine the effects of supplemental dietary antioxidants in vivo, we evaluated(More)
Single-chain Fv (scFv) molecules exhibit highly specific tumour-targeting properties in tumour-bearing mice. However, because of their smaller size and monovalent binding, the quantities of radiolabelled scFv retained in tumours limit their therapeutic applications. Diabodies are dimeric antibody-based molecules composed of two non-covalently associated(More)
The use of archived injormatiori arid knowledge derived from data-driven system, both at the poirit of care and retrospectively, is critical to iniproving the balance between healthcare e.rperiditure arid healthcare qirality. Data-driveti clinical decision support, augmented by pe$orinance feedback arid edircatiori, is a logical addition to consensus arid(More)
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