Raymond R. R. Rowland

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1 To the Editor: Porcine reproductive and respiratory syndrome (PRRS) is the most economically important disease of swine in North America, Europe and Asia, costing producers in North America more than $600 million annually 1. The disease syndrome was first recognized in the United States in 1987 and described in 1989 (ref. 2). The causative agent, porcine(More)
Infections caused by porcine reproductive and respiratory syndrome virus (PRRSV) have a severe economic impact on pig production in North America, Europe, and Asia. The emergence and eventual predominance of PRRS in the 1990s are the likely result of changes in the pork industry initiated in the late 1970s, which allowed the virus to occupy a unique niche(More)
Macrophages (MФs) can be polarized to various activation statuses, including classical (M1), alternative (M2), and antiviral states. To study the antiviral activation status of porcine MФs during porcine reproductive and respiratory syndrome virus (PRRSV) infection, we used RNA Sequencing (RNA-Seq) for transcriptomic analysis of differentially expressed(More)
  • Kyle P Horlen, Paula Schneider, Joseph Anderson, Jerome C Nietfeld, Diplomate Acvp, Steven C Henry +4 others
  • 2007
The objective of this study was to characterize the clinical, histopathological, and virological features of an outbreak of severe porcine circovirus associated disease (PCVAD) on four farms located in the same geographical region of Kansas. The outbreak of PCVAD was evident by increased mortality and the appearance of postweaning multisystemic wasting(More)
BACKGROUND Since the first pandemic 2009 H1N1 (pH1N1) virus was isolated from humans, it has also been detected in other mammalian (pigs, cats, dogs, ferrets) and avian (turkey) species, most likely because of cross-species transmission from humans. The pH1N1 contains six genes derived from swine influenza viruses (SIVs) currently circulating in North(More)
Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically significant viral diseases facing the global swine industry. Viremia profiles of PRRS virus challenged pigs reflect the severity and progression of infection within the host and provide crucial information for subsequent control measures. In this study we analyse the(More)
The arteriviruses (Family Arteriviridae, Genus Arterivirus) include an interesting group of enveloped positive stranded RNA viruses that infect domestic and wild animals and they share a strikingly similar genome organization and replication strategy to that of coronaviruses, but differ considerably in their genetic complexity and virion architecture. Until(More)
Porcine reproductive and respiratory syndrome virus (PRRSV) can subvert early innate immunity, which leads to ineffective antimicrobial responses. Overcoming immune subversion is critical for developing vaccines and other measures to control this devastating swine virus. The overall goal of this work was to enhance innate and adaptive immunity following(More)
  • Megan L Potter, Lisa M Tokach, Steve S Dritz, Steven C Henry, Joel M Derouchey, Mike D Tokach +8 others
  • 2011
Potter ML, Tokach LM, Dritz SS, et al. Genetic line influences pig growth rate responses to vaccination for porcine circovirus type 2. Summary Objectives: To compare the effects of porcine circovirus type 2 (PCV2) vaccination on growth rate, backfat depth, and loin depth of pigs in a high-health herd which contained different genetic lines. Materials and(More)
Porcine reproductive and respiratory syndrome (PRRS) is one of the most important swine diseases in the world and genetic selection of pigs for increased resistance to PRRS is an attractive method to improve the health status of the swine herd. This study compared phenotypic and genetic responses to infection with one of two genetically distinct type 2 PRRS(More)