Raymond L. Rodriguez

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BACKGROUND Life processes are determined by the organism's genetic profile and multiple environmental variables. However the interaction between these factors is inherently non-linear. Microarray data is one representation of the nonlinear interactions among genes and genes and environmental factors. Still most microarray studies use linear methods for the(More)
  • Molecular Biosciences, Ted Powers, Jawdat Al-Bassam, John Assistant, Albeck, Enoch Baldwin +71 others
  • 2014
Molecular and Cellular Biology offers three major programs: Biochemistry and Molecular Biology, Cell Biology, and Genetics and Genomics. The Biochemistry and Molecular Biology major introduces students to the chemistry of living organisms and the experimental techniques that are used to probe the structures and functions of biologically important molecules.(More)
Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter(More)
BACKGROUND The aberrant regulation of phosphatidylinositide 3-kinases (PI3-K)/Akt, AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (m-TOR) signaling pathways in cancer has prompted significant interest in the suppression of these pathways to treat cancer. Caffeic acid (CA) has been reported to possess important anti-inflammatory(More)
  • Jasmine M. Corbin, Bryce I. Hashimoto, Kalimuthu Karuppanan, Zachary R. Kyser, Liying Wu, Brian A. Roberts +4 others
  • 2016
An active and tetrameric form of recombinant butyrylcholinesterase (BChE), a large and complex human enzyme, was produced via semicontinuous operation in a transgenic rice cell suspension culture. After transformation of rice callus and screening of transformants, the cultures were scaled up from culture flask to a lab scale bioreactor. The bioreactor was(More)
To optimize the expression, extraction and purification of plant-derived tetrameric recombinant human butyrylcholinesterase (prBChE), we describe the development and use of plant viral amplicon-based gene expression system; Tobacco Mosaic Virus (TMV) RNA-based overexpression vector (TRBO) to express enzymatically active FLAG-tagged plant made recombinant(More)
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