Raymond K Reichwein

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OBJECTIVE Electrodiagnostic testing (electromyography [EMG] and nerve conduction studies [NCS]) may result in some patient discomfort. The justification for such testing should be based on the expectation that the results will affect patient management. This study was conducted to determine how frequently the results of EMG/NCS change the clinical(More)
Cutaneous malignancies may spread to underlying nerves, a process known as perineural invasion (PNI). We report a patient who was found to have PNI presenting as a cranial polyneuropathy on the contralateral side of the face many years after the resection of a squamous cell carcinoma. All diagnostic testing was unrevealing until nerve biopsy was performed.(More)
Peripheral nerve involvement is a rare, yet treatable neurological manifestation of sarcoidosis. Most patients respond well to corticosteroids, but relapses are common and the long-term prognosis remains unpredictable. We present a patient with an asymmetrical neurological presentation of previously undiagnosed sarcoidosis. She presented with paresthesias(More)
INTRODUCTION Decompressive craniectomy has demonstrated efficacy in reducing morbidity and mortality in critically ill patients with massive hemispheric cerebral infarction. However, little is known about the patterns of functional recovery that exist in patients after decompressive craniectomy, and controversy still exists as to whether craniotomy and(More)
Bioassay-guided fractionation of the EtOAc extract of the Palauan sponge Axinyssa aplysinoides yielded two novel alkaloids, 1 and 2. The structure of 2-(formylamino)trachyopsane (1) was determined by X-ray analysis; and the structure of N-phenethyl-N'-2-trachyopsanylurea (2), by interpretation of the spectral data.
Objective: To provide external validation of the DRAGON Score for predicting outcome after intravenous thrombolysis Methods: A retrospective chart analysis was performed in stroke patients receiving IV-tPA within the 4.5 hour time window from January 2009 to September 2013. A total of 149 patients were included in the analysis. DRAGON scores were calculated(More)
OBJECTIVE Reporting a novel mutation in the HTRA1 gene in a CARASIL patient from Americas. METHODS Clinical presentation and neuroimaging were consistent with CARASIL. HTRA1 DNA sequencing was performed using advanced ("next generation") sequencing technology. The results revealed a homozygous missense mutation as c.616G>A (p.Gly206Arg) in the HTRA1 gene.(More)
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