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Recent studies have shown that lateral pharyngoplasty is an effective procedure to correct obstructive sleep apnea. The objective of the paper was to evaluate factors contributing to obstructive sleep apnea syndrome and identify the different severity categories of obstructive sleep apnea that could benefit from lateral pharyngoplasty. We included 60(More)
In this study, we examined the relationships between p38 mitogen-activated protein kinase (MAPK) activation in the cuneate nucleus (CN) and behavioral hypersensitivity after chronic constriction injury (CCI) of the median nerve. We further investigated effects of melatonin administration and pinealectomy on p38 MAPK activation and development of(More)
In this study, we examined the relationship between astrocyte activation in the cuneate nucleus (CN) and behavioral hypersensitivity after chronic constriction injury (CCI) of the median nerve. In addition, we also examined the effects of pre-emptive treatment with a number of drugs on astrocyte activation and hypersensitivity development in this model.(More)
STUDY OBJECTIVES To quantify the prevalence of self-reported near-miss sleepy driving accidents and their association with self-reported actual driving accidents. DESIGN A prospective cross-sectional internet-linked survey on driving behaviors. SETTING Dateline NBC News website. RESULTS Results are given on 35,217 (88% of sample) individuals with a(More)
Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder that leads to significant morbidity and mortality without adequate treatment. Though much emphasis on the pathogenesis of OSAS has been placed on a narrow upper airway space and associated muscular factors, possible neuropathy of the upper airway has not been fully elucidated. Increasing(More)
Lemierre syndrome is an extremely rare disease characterized by oropharyngeal infection, septicemia, internal jugular vein thrombosis, and skip lesions. The most common causative pathogen is Fusobacterium necrophorum. We reported a 45-year-old woman who presented with left neck painful swelling and septicemia. Magnetic resonance imaging of the head and neck(More)
STUDY OBJECTIVES Sleep deprivation is common in patients with neuropathic pain, but the effect of sleep deprivation on pathological pain remains uncertain. This study investigated whether sleep deprivation aggravates neuropathic symptoms and enhances microglial activation in the cuneate nucleus (CN) in a median nerve chronic constriction injury (CCI) model.(More)
OBJECTIVE Although various instruments have been developed to evaluate insomniac symptoms in individuals, none of them are based on the International Classification of Sleep Disorder, 2nd (ICSD-II). The purpose of this study is to develop a new scaling system, the Insomnia Screening Scale (ISS) to fit the new diagnostic criteria. METHODS Study 1 was(More)
OBJECTIVES/HYPOTHESIS Pediatric obstructive sleep apnea syndrome (OSAS) is a common disorder with serious clinical implications if left untreated. The recommended initial treatment for pediatric patients with obstructive sleep apnea syndrome (OSAS) is adenotonsillectomy. However, recent reports have shown variable surgical results with adenotonsillectomy in(More)
A prototype of Sleep Coach was developed to resolve long-lasting problems of cognitive behavioral therapy for insomnia patients: low compliance and low levels of patient feedback. Sleep Coach, designed to function like an ordinary book, provides a diary module to remind patients to log sleep-related activities and a training module for helping patients(More)