Rayime Wegner

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PURPOSE To evaluate the expression of melanoma cell adhesion molecule (MCAM) as prognostic factor in uveal melanoma patients. METHODS Paraffin sections from 35 primary uveal melanomas were analyzed immunhistochemically for the expression of MCAM. Further known prognostic factors such as cell type, ciliary body invasion, tumor stage, and local extension(More)
Endoglin/CD105 is a transmembrane regulatory receptor for transforming growth factor-β (TGF-β) that is predominantly expressed on proliferating endothelial cells (ECs) in culture and on angiogenic blood vessels in vivo. Endoglin has been associated with angiogenesis and prognosis in several malignancies. Although microvascular structure has been(More)
This article provides a review of one patient's experience with prostate cancer. It examines the various aspects of the decision-making process-the discovery of the disease, the research undertaken to learn about the disease and the treatment options, the decision as to course of action, the resultant radical prostatectomy, and the short- and long-term(More)
PURPOSE To evaluate the concurrent rate of expression of c-Kit and its ligand stem cell factor (SCF) in uveal melanoma in respect to the further clinical course and the correlation of these markers. METHODS Paraffin sections from 35 primary uveal melanomas were evaluated immunohistochemically for the expression of c-Kit and SCF. Sixteen cases developed(More)
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