Csaba Vadasz4
Mariko Saito4
Danielle O'Brien3
4Csaba Vadasz
4Mariko Saito
3Danielle O'Brien
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OBJECTIVE To add to the evidence on comparative long-term effects of insulin analog glargine versus human NPH insulin on the risk for cancer. RESEARCH DESIGN AND METHODS We identified cohorts of initiators of glargine and human NPH without an insulin prescription during the prior 19 months among patients covered by the Inovalon Medical Outcomes Research(More)
BACKGROUND Although a large body of evidence suggests a role for the opioid system in alcoholism, the precise role of mu-, delta-, kappa-, and ORL1-opioid receptors and the physiological significance of their natural genetic variation have not been identified. The method of targeted gene disruption by homologous recombination has been used to knock out (KO)(More)
BACKGROUND Ethanol exposure induces apoptotic neurodegeneration in the developing rodent brain during synaptogenesis. This process has been studied as a model for fetal alcohol syndrome. Previously, we have shown that gangliosides and LIGA20 (a semisynthetic derivative of GM1 ganglioside) attenuate ethanol-induced apoptosis in cultured neurons. In the(More)
The aim of this study was to identify neurochemical pathways and candidate genes involved in adaptation to nicotine treatment and withdrawal. Locomotor sensitization was assessed in a nicotine challenge test after exposure to intermittent nicotine treatment and withdrawal. About 24 h after the challenge test the ventral tegmentum of the mesencephaion was(More)
  • Research Showcase, Cmu, German Andrés, Oliveros Patiño, Carnegie Mellon University, B Erik +11 others
  • 2015
This thesis contains a theoretical analysis of the Horizontal Ribbon Growth (HRG) process for growing silicon wafers. In the HRG process, a thin silicon ribbon is crystallized and extracted continuously from the melt, using the fact that silicon floats on its melt just like ice floats on top of water. In our work, we assess two technical issues reported in(More)
OBJECTIVES To compute a benchmark for tracking readmission rates among patients enrolled in Medicare's private comprehensive Medicare Advantage (MA) plans and to develop preliminary comparisons with the fee-for-service (FFS) readmission rates. STUDY DESIGN Descriptive data presentation with analytic discussion. METHODS We computed a benchmark for(More)
This study proposes a holistic approach for determining critical attributes in e-learning measurements. There is an abundance of literature pertaining to the e-learning framework, but there is a shortage of literature on how to properly implement the framework in uncertainty with variance and interactive relationships. This paper also considers the nature(More)
It is believed that drug-induced behavioral sensitization is an important process in the development of substance dependence. In order to explore mechanisms of sensitization, a mouse model of nicotine-induced locomotor sensitization was established, and effects of the sensitization process on mesencepahlic gene expression were examined. A schedule, which(More)
Diicult computations can be made more eeective and eecient if users can easily contribute to the problems these computations address. This article's purpose is an introduction to the potential increases in functionality and performance gained by the online interaction of end users with high performance computational instruments on single and on networked(More)