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BACKGROUND The Contact Heat Evoked Potential Stimulator (CHEPS) utilises rapidly delivered heat pulses with adjustable peak temperatures to stimulate the differential warm/heat thresholds of receptors expressed by Adelta and C fibres. The resulting evoked potentials can be recorded and measured, providing a useful clinical tool for the study of thermal and(More)
OBJECTIVE To assess the temporal relationship between skin nerve denervation and regeneration (dermal and intra-epidermal fibres, IENF) and functional changes (CO(2) laser-evoked potentials, LEPs, and quantitative sensory tests, QST) after topical cutaneous application of capsaicin. METHODS Capsaicin (0.075%) was applied to the lateral calf for three(More)
Tumours represent one of the important differential diagnoses that need to be considered while investigating fractures of the small bones of the hand, as this can sometimes be the sole or the first presenting complaint. We conducted a retrospective study of the Scottish Bone Tumour Registry, analysing the records of patients with hand tumours which(More)
BACKGROUND A variation seems to exist between hospitals with regard to the initial radiographic assessment of suspected scaphoid fractures. MATERIALS AND METHODS A survey of all acute hospitals in the West of Scotland was carried out to ascertain the current practice in the assessment of acute scaphoid fractures. Consultant radiologists and consultant(More)
BACKGROUND Intracranial haemorrhage accounts for 30-60 % of all stroke admissions into a hospital, with hypertension being the main risk factor. Presence of intraventricular haematoma is considered a poor prognostic factor due to the resultant obstruction to CSF and the mass effect following the presence of blood resulting in raised intracranial pressure(More)
BACKGROUND Endoscopic third ventriculostomy (ETV) is a procedure of choice in the treatment of obstructive hydrocephalus. Neurovascular injury while perforating the ventricular floor can occur when using a conventional probe, especially in patients with a thick and opaque third ventricle floor. The water jet dissection technique can be useful in such cases(More)
Current treatments of neuropathic pain arising from conditions such as nerve injury/compression are only partially effective, and limited in their use by side-effects. p38 mitogen-activated protein kinase (MAPK) is involved in the regulation and synthesis of inflammatory mediators, and is the target for a novel class of cytokine-suppressive(More)
Posterior dislocations of the shoulder joint can result in an impression fracture over the anteromedial humeral head, termed the reverse Hill-Sachs lesion, the presence of which can contribute to recurrent dislocations. Methods described to repair this defect include using allografts, iliac crest and coracoid process autografts, and bone graft substitutes.(More)
Management of osteosarcoma has evolved during the last 50 years. A review of 53 cases of osteosarcoma affecting the humerus included in the Scottish Bone Tumour registry from 1950 to 2000 is presented. Survival trends and the various factors influencing survival during this period are analysed. Patients were chronologically divided into two cohorts, one(More)
INTRODUCTION Associated with the increase in the aging population, there is an increase in the incidence of hip fractures worldwide. Outcome following such fractures is affected by age of the patient. This study aims to assess the incidence and early outcome of hip fractures, comparing between different age groups. METHODS Data of hip fractures collected(More)