RaulC. Braylan

  • Citations Per Year
Learn More
The peripheral blood lymphoid cells of five patients with Sézary syndrome (SS) were examined with respect to their surface membrane characteristics and their response to mitogens. These cells showed markedly defective mitogenic responses to a broad dose range of phytohaemagglutinin (PHA), pokeweed mitogen, concanavalin A, and a rabbit antihuman lymphocyte(More)
Eight cases of 'hairy' cell leukaemia (leukaemic reticuloendotheliosis) were evaluated by scanning electron microscopy. The surface of critical-point-dried 'hairy' cells was characterized by prominent and exaggerated broad-based, ruffled membranes and scattered small clusters of stub-like microvilli. The surface morphology resembled that of normal and(More)
Electron microscopic findings in 15 cases of diffuse large cell lymphoma were correlated with other morphologic features, surface immunotype and cytoplasmic immunoglobulin content. Immunologically, the cases were: B cell, 8; null, 4; T cell, 2; and H cell (true histiocytic), 1. Ultrastructurally, all B cell and three null lymphomas were characterized by an(More)
Peripheral blood mononuclear cells from a patient with Sézary syndrome which lacked E-rosette-forming ability and surface immunoglobulins, and which displayed a markedly depressed response to a variety of mitogens, were studied by scanning electron microscopy (SEM) and transmission electron microscopy (TEM) on 3 occasions. The first peripheral blood sample(More)
The microbial iron chelator vibriobactin, N-[3-(2,3-dihydroxybenzamido)propyl]-1,3-bis[2-(2, 3-dihydroxyphenyl)-trans-5-methyl-2-oxazoline-4-carboxamido]-propane, is shown to inhibit the growth of L1210 cells in culture, with an IC50 value of 2 microM. Its biological activity is assigned to the ligand's ability to chelate iron as indicated by the(More)
Flow cytometric analysis of DNA of tumor cells rapidly provides information on cell kinetics and tumor ploidy. Human B-cell lymphomas, however, often contain high numbers of nonneoplastic cells, mainly T-lymphocytes, which may hamper the ac curate measurement of cell cycle phases and ploidy level of these tumors. The neoplastic cells in each B-cell lymphoma(More)
  • 1