Raul Rodriguez-Esteban

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In European research today, mobility has become firmly entrenched as a pre requisite for a successful scientific career; however, the reasons behind this emphasis on scientific nomadism are far from obvious. It is all too common for science policy-makers and funding bodies to extol the seemingly endless virtues of mobility, but it nearly amounts to heresy(More)
Scientific enterprise is not just a quest for knowledge and truth; it is also a fairly good reflection of the whole spectrum of human behaviour: from genius, passion and jealousy, to mistakes and misconduct. although new scientific advances and insights are always exciting, the reaction of many scientists to mistakes and misconduct—and to the accompanying(More)
We describe a new tool for visualization of biomedical scientific trends. The method captures variations in scientific impact over time to allow for a comparison of relative significance and evolution of fields similar to a financial market scorecard. The tool is available at SciTrends (http://www.scitrends.net), depicting the evolution of almost 200(More)
This tutorial is intended for biologists and computational biologists interested in adding text mining tools to their bioinformatics toolbox. As an illustrative example, the tutorial examines the relationship between progressive multifocal leukoencephalopathy (PML) and antibodies. Recent cases of PML have been associated to the administration of some(More)
One drug may suppress the effects of another. Although knowledge of drug suppression is vital to avoid efficacy-reducing drug interactions or discover countermeasures for chemical toxins, drug-drug suppression relationships have not been systematically mapped. Here, we analyze the growth response of Saccharomyces cerevisiae to anti-fungal compound ("drug")(More)
Text-mining algorithms make mistakes in extracting facts from natural-language texts. In biomedical applications, which rely on use of text-mined data, it is critical to assess the quality (the probability that the message is correctly extracted) of individual facts--to resolve data conflicts and inconsistencies. Using a large set of almost 100,000 manually(More)
We have generated and made publicly available two very large networks of molecular interactions: 49,493 mouse-specific and 52,518 human-specific interactions. These networks were generated through automated analysis of 368,331 full-text research articles and 8,039,972 article abstracts from the PubMed database, using the GeneWays system. Our networks cover(More)
Text mining services are rapidly becoming a crucial component of various knowledge management pipelines, for example in the process of database curation, or for exploration and enrichment of biomedical data within the pharmaceutical industry. Traditional architectures, based on monolithic applications, do not offer sufficient flexibility for a wide range of(More)
Fully automated text mining (TM) systems promote efficient literature searching, retrieval, and review but are not sufficient to produce ready-to-consume curated documents. These systems are not meant to replace biocurators, but instead to assist them in one or more literature curation steps. To do so, the user interface is an important aspect that needs to(More)