Raul Muñoz-Hernandez

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Background The Calcium Dependent Antibiotic (CDA) from S. coelicolor is a non-ribosomally synthesised lipopeptide which consists of 11 amino acids to which a lipid part has been attached [1]. Although the mode of action for CDA is not yet known, antibiotics with similar structure like daptomycin or friulimicin inhibit bacterial cell wall synthesis.(More)
Background Cosmomycin, an aromatic polyketide antibiotic complex produced by Streptomyces olindensis, belongs to anthracycline family of chemotherapy drugs. It is a powerful antitumor drug similar to doxorubicin and daunorubicin. The structure of cosmomycin consists of one tetracycline aglycon (β-rhodomycinone) and six deoxysugars (two dTDPL-2-deoxifucose,(More)
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