Raul Florin Horhat

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In this paper we analyze a simple mathematical model which describes the interaction between the proteins p53 and Mdm2. For the stationary state we discuss the local stability and the existence of the Hopf bifurcation. Choosing the delay as a bifurcation parameter we study the direction and stability of the bifurcating periodic solutions. Some numerical(More)
p53 gene is a central hub in a network that have the role to protect the cells against carcinogenesis. A lot of research work has been done in this field, a huge amount of data was collected and many experiments have been performed. For a better understanding of the processes and for the help of experiments design some mathematical models were proposed in(More)
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