Rashid A. Bhatti

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BACKGROUND Recessive mutant alleles of MYO7A, USH1C, CDH23, and PCDH15 cause non-syndromic deafness or type 1 Usher syndrome (USH1) characterised by deafness, vestibular areflexia, and vision loss due to retinitis pigmentosa. For CDH23, encoding cadherin 23, non-syndromic DFNB12 deafness is associated primarily with missense mutations hypothesised to have(More)
We ascertained two large Pakistani consanguineous families (PKDF231 and PKDF608) segregating profound hearing loss, vestibular dysfunction, and retinitis pigmentosa; the defining features of Usher syndrome type 1 (USH1). To date, seven USH1 loci have been reported. Here, we map a novel locus, USH1K, on chromosome 10p11.21-q21.1. In family PKDF231, we(More)
The object of the present investigations was delineation of the exclusive effects of cyclophosphamide (Cytoxan) on host humoral response to tumor, as evaluated by the level of circulating antigen/antibody complexes (AACs), which may reflect the chemo-responsiveness of hosts and provide a rationale for new therapeutic strategies. Our data, recorded in(More)
Circulating immune complexes in the sera of patients with confirmed histological diagnosis of carcinoma of the prostate, were found to interfere in the sensitized leukocyte's in vitro reactivity to prostate cancer associated antigen as evaluated by tube leukocyte adherence inhibition assay, thereby suggesting an inhibitory role of such serum factors in(More)
Mobile convergence is an emerging trend in the wireless communication industry. Modern multi-standard mobile phones are required to provide a variety of location independent services like voice, data, video, the Internet and multimedia content without compromising on their weight, volume and performance. Therefore, it is important to develop compact(More)
Performance of MIMO-enabled portable devices is heavily dependent on the characteristics of its antenna arrays [1]-[2]. A typical MIMO antenna array for portable devices should have compact structure, high radiation efficiency, and low spatial correlation in addition to the required bandwidth and nearly omni-directional radiation pattern. Various MIMO(More)
A peptide (NH2-Ser-Glu-Lys-Ser-Glu-Glu-Ile-Asn-Glu-Lys-Gly-Lys) from the N-terminal sequence of staphylococcal enterotoxin A (SEA) was synthesized and conjugated to bovine serum albumin (BSA). When injected into rabbits, this conjugate induced antibodies which reacted with the native SEA molecule. These antibodies did not cross-react with other(More)
Recently, research interest has increased in the design, development, and deployment of microstrip antenna agent systems for high-level inference and surveillance in a wireless sensor network (WSN). The proposed Antenna agent systems employ migrating codes to facilitate flexible application retasking, local processing, and calculating parameters. This(More)