Rasheedah Ahmad

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The role of reactive oxygen species (ROS)-damaged human serum albumin (HSA) in lung cancer (LC) patients is investigated. The binding characteristics of LC antibodies with native and ROS-damaged HSA are assessed. Smoking and non-smoking LC patients (n=40) are examined by a direct binding enzyme-linked immunosorbent assay (ELISA) and the results are compared(More)
Reactive oxygen species (ROS) are formed in living organisms during normal metabolic reactions as well as under different environmental stresses. In this study, thymidine monophosphate (TMP) was exposed to hydroxyl radical (OH) and challenged in rabbits. TMP and OH-modified TMP were found to be nonimmunogenic. The TMP was linked to bovine serum albumin(More)
The role of reactive oxygen species (ROS) damaged human serum albumin (HSA) in hepatocellular carcinoma (HCC) has been investigated in the present study. HSA was modified by hydroxyl radical. Modification occurred in HSA was characterized by physico-chemical techniques. ROS modified HSA was found to be highly immunogenic in rabbits. The binding(More)
Monocyte heterogeneity has been studied extensively in man but only recently tools have been developed to study blood monocyte populations in the mouse. We have used the MacGreen mouse model, which expresses the green fluorescent protein under the control of the promoter of the murine M-CSF receptor (CSF1 receptor, c-fms). Since both monocytes and(More)
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