Raquel Vaz

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Myogenesis is a complex process in which committed myogenic cells differentiate and fuse into myotubes that mature into the muscle fibres of adult organisms. This process is initiated by a cascade of myogenic regulatory factors expressed upon entry of the cells into the myogenic differentiation programme. However, external signals such as those provided by(More)
Mutations in the co-chaperone Bcl2-associated athanogene 3 (BAG3) can cause myofibrillar myopathy (MFM), a childhood-onset progressive muscle disease, characterized by the formation of protein aggregates and myofibrillar disintegration. In contrast to other MFM-causing proteins, BAG3 has no direct structural role, but regulates autophagy and the degradation(More)
INTRODUCTION Sarcoidosis is a systemic granulomatous disease. Renal involvement is a rare initial presentation of this disease. Few articles on renal involvement as an initial presentation of sarcoidosis have been published in the literature. CASE PRESENTATION A 26-year-old Caucasian woman presented with acute renal failure as an initial manifestation of(More)
  • Andreia Barbosa Valença, Andreia Barbosa, Valença Dissertação Orientada Por, Orientador Externo, Doutora, Jodi Pawluski +12 others
  • 2010
2010 i Acknowledgements I would like to thank everyone that in one way or another took part in this big journey: Dr. Jodi Pawluski, for her guidance, knowledge, encouragement, patience, time and wise advices throughout the elaboration of this thesis. Besides being my supervisor, her friendship along the way was very important. Dr. Tatyana Strekalova, for(More)
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