Raquel Rodrigues Vaz

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Myogenesis is a complex process in which committed myogenic cells differentiate and fuse into myotubes that mature into the muscle fibres of adult organisms. This process is initiated by a cascade of myogenic regulatory factors expressed upon entry of the cells into the myogenic differentiation programme. However, external signals such as those provided by(More)
INTRODUCTION Sarcoidosis is a systemic granulomatous disease. Renal involvement is a rare initial presentation of this disease. Few articles on renal involvement as an initial presentation of sarcoidosis have been published in the literature. CASE PRESENTATION A 26-year-old Caucasian woman presented with acute renal failure as an initial manifestation of(More)
BACKGROUND Skeletal myogenesis is extensively influenced by the surrounding environment. However, how the extracellular matrix (ECM) affects morphogenesis of muscles is not well understood. RESULTS We mapped the three-dimensional (3D) organization of fibronectin, tenascin, and laminin by immunofluorescence during early epaxial myogenesis in mouse embryos.(More)
BACKGROUND AND OBJECTIVES For many women pregnancy is the first contact with health services, thus providing an opportunity to identify renal disease. This study compares causes and long-term renal outcomes of biopsy-proven renal disease identified during pregnancy or within 1 year postpartum, with nonpregnant women. DESIGN, SETTING, PARTICIPANTS, &(More)
Anemia in Chronic Kidney Disease (CKD) is present in approximately 90% of patients with glomerular filtration rate below 25-30 mL/min. It's impact in the quality of life makes it one of the major problems in CKD patients. Although the etiology is multifactorial the suboptimal production of erithropoietin caused by renal mass loss appears to be of major(More)
Renalase is a recently described enzyme secreted by the kidney into both plasma and urine, where it was suggested to degrade catecholamines contributing to blood pressure control. While there is a controversy regarding the relationship between renal function and plasma renalase levels, there is virtually no data in humans on plasma renalase activity as well(More)
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