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Cell-Type-Specific TEV Protease Cleavage Reveals Cohesin Functions in Drosophila Neurons

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Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei

It is concluded that only two key events, opening of cohesin rings and downregulation of Cdk1, are sufficient to drive proper segregation of chromosomes in anaphase.
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Disengaging the Smc3/kleisin interface releases cohesin from Drosophila chromosomes during interphase and mitosis

It is shown that Wapl‐dependent release from salivary gland polytene chromosomes during interphase and from neuroblast chromosome arms during prophase is blocked by translational fusion of Smc3's C‐ terminus to kleisin's N‐terminus.
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A Direct Role for Cohesin in Gene Regulation and Ecdysone Response in Drosophila Salivary Glands

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The Condensin I Subunit Barren/CAP-H Is Essential for the Structural Integrity of Centromeric Heterochromatin during Mitosis

The data suggest that the condensin I complex is required not only to promote sister chromatid resolution but also to maintain the structural integrity of centromeric heterochromatin during mitosis.
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Cohesin cleavage is insufficient for centriole disengagement in Drosophila

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Metaphase chromosome structure is dynamically maintained by condensin I-directed DNA (de)catenation

It is proposed that maintenance of chromosome resolution is a highly dynamic bidirectional process that is capable of re-intertwining previously separated DNA molecules and condensin I continuously required to counteract this erroneous activity.
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Condensin I binds chromatin early in prophase and displays a highly dynamic association with Drosophila mitotic chromosomes

The results suggest that in Drosophila, condensin I is involved in the initial stages of chromosome condensation, and the rapid turnover of Barren-EGFP indicates that the mechanism by which condens in I promotes mitotic chromosome organization is inconsistent with a static scaffold model.
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Novel insights into mitotic chromosome condensation

Various models for chromosome assembly and known factors involved in the condensation process are introduced and a few selected studies that have recently brought novel insights into the mysterious way chromosomes are condensed during nuclear division are focused on.
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Getting through anaphase: splitting the sisters and beyond.

The nature of the cohesive forces that hold sister chromatid together, the mechanisms that trigger their physical separation, and the anaphase-specific changes that ensure proper segregation of single chromatids during the later stages of mitosis are discussed.
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